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CAZyme Information: MGYG000001643_01997
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-485; | |||||||||||
| CAZyme ID | MGYG000001643_01997 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Retaining alpha-galactosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 18201; End: 19958 Strand: + | |||||||||||
Full Sequence Download help
| MVIKGIALLS FFVCSVSSWG FVSPNGKFVV DEIPSGLAFT MLHEDGKTIP FLELRCEGTE | 60 |
| EVGACGPVEV SYEMKIGKKS SCKNEYNERH YLLPEGDTLS VRLFNDGVAW KKRGASSIRF | 120 |
| LNPSHHWLQS WKDCYEDFFP ADGEIREGAR YGYPALLEFG EGRFALLSES GITPEDAATS | 180 |
| MHSTGGYGFD LVPDGSENGG WQTVIAGSLY DVVESTLVTD NSHPALTEDA SWVMPGVASW | 240 |
| VYWAYNHGSN DYNIIKKYVD LAVSLKLPYV LIDAEWDEMK DGKSIEDAVA YARSKGVKPM | 300 |
| IWYNSSVGWV NGAPGPKYRL NTAENLEKEF KWCEDLGITG VKIDFFSGDT NMNLRFMAEL | 360 |
| LEAAARHHLT VNFHGATLPR GWQRTYPNLV SVEAVYGAEW YNNVPTFTEK AACHNATLPF | 420 |
| TRNVVGSMDY TPCAFSDSQH PHITTHAHEL ALTSLFESGI QHIADRPESI LAQPEEVRGY | 480 |
| ISDLPAAWDD TKLLGGYPGK YAAVARKKGD RWWIAVINGT DEPIYDLRLD FSRIIPEGKG | 540 |
| VEGIMFEDSY DKGEGDWKIS RITGLPDSIT LQPRGGMTCV VKMKK | 585 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 68 | 577 | 1.4e-121 | 0.8716323296354992 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam10566 | Glyco_hydro_97 | 1.01e-83 | 229 | 485 | 1 | 278 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14509 | GH97_C | 2.65e-19 | 488 | 577 | 1 | 92 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
| pfam14508 | GH97_N | 9.43e-15 | 22 | 220 | 22 | 231 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADE81739.1 | 7.49e-207 | 15 | 585 | 16 | 621 |
| QVJ82067.1 | 8.03e-206 | 15 | 582 | 17 | 619 |
| QCD34511.1 | 4.29e-203 | 23 | 582 | 25 | 609 |
| ADI70675.1 | 4.46e-200 | 22 | 582 | 44 | 627 |
| ALJ60079.1 | 1.83e-170 | 14 | 582 | 19 | 630 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5XFM_A | 3.15e-72 | 22 | 580 | 42 | 641 | Crystalstructure of beta-arabinopyranosidase [Bacteroides thetaiotaomicron],5XFM_B Crystal structure of beta-arabinopyranosidase [Bacteroides thetaiotaomicron],5XFM_C Crystal structure of beta-arabinopyranosidase [Bacteroides thetaiotaomicron],5XFM_D Crystal structure of beta-arabinopyranosidase [Bacteroides thetaiotaomicron] |
| 3A24_A | 1.52e-35 | 25 | 582 | 28 | 641 | Crystalstructure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron],3A24_B Crystal structure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron] |
| 5E1Q_A | 1.35e-34 | 25 | 582 | 42 | 655 | Mutant(D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482],5E1Q_B Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482] |
| 5HQC_A | 1.39e-25 | 72 | 574 | 66 | 636 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQ4_A | 1.85e-25 | 72 | 574 | 66 | 636 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| D7CFN7 | 1.09e-70 | 22 | 581 | 63 | 608 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
| Q8A6L0 | 9.55e-35 | 25 | 582 | 49 | 662 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| G8JZS4 | 1.15e-23 | 77 | 558 | 115 | 690 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.093635 | 0.895948 | 0.009494 | 0.000308 | 0.000272 | 0.000317 |