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CAZyme Information: MGYG000001652_00447

You are here: Home > Sequence: MGYG000001652_00447

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species V9D3004 sp002349525
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; V9D3004; V9D3004 sp002349525
CAZyme ID MGYG000001652_00447
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1049 120776.67 8.4746
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001652 2035634 MAG United States North America
Gene Location Start: 19171;  End: 22320  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001652_00447.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 632 861 2.7e-54 0.9237668161434978

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 5.26e-33 872 1043 2 198
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG1928 PMT1 6.91e-23 873 1045 501 693
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
COG5542 COG5542 2.90e-18 66 341 92 359
Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism].
pfam02366 PMT 2.36e-11 629 805 14 204
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG4346 COG4346 7.50e-10 649 999 126 414
Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCN30459.1 0.0 19 1048 45 1059
QNM01664.1 1.22e-288 23 1048 42 1086
BBF42044.1 1.13e-270 114 1048 2 921
AIQ66842.1 7.02e-210 23 1045 18 1029
AIQ15817.1 1.09e-208 19 1045 14 1029

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
L8F4Z2 5.58e-25 638 1045 67 515
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
Q8NRZ6 4.23e-22 660 1045 98 519
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1
P9WN04 5.71e-22 638 1045 73 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 5.71e-22 638 1045 73 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
Q5ACU3 1.33e-08 870 1045 515 716
Dolichyl-phosphate-mannose--protein mannosyltransferase 5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT5 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999771 0.000206 0.000002 0.000001 0.000001 0.000020

TMHMM  Annotations      download full data without filtering help

start end
13 35
94 116
123 142
146 168
175 197
217 239
283 300
310 327
351 373
383 404
476 495
680 702
709 726
731 753
765 782
786 803
839 861
929 946
953 970
975 997
1009 1031