CAZyme Information: MGYG000001666_00410

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-873
• CAZyme ID: MGYG000001666_00410
• CAZy Family: GH76
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
678	MGYG000001666_12|CGC1	75052.71	4.9609

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001666	2832137	MAG	United States	North America

• Gene Location: Start: 24881; End: 26917 Strand: +

Full Sequence      

MTCIATASALTPGVAYSVGQHGRSVFISNGRPDRNADVQMWTDTDVPAQRWVLEQSDTDP
RQYALRNLFSGLYLNYNGTRAGAKIRQADRSVFSSYWTLEEDGDSYVLVPSQNAAMCLAA
ASTDEGAALSLQERAAADAGLTRFTLRQDDVPEAFGEAVRDDFMSGFLGQYYHKASTGHV
LGGGGWWGDAEMFEVILDAFATTGDLKYKEIFDELVIDFCRRNGRDWSNNEFNDDITWMV
LACARAYKYFGTQEYLDLAKDNYTRMYNRAHQRFGTLIWKQSQENKIATNSCINCPATVA
ACMLGELTGDNSWYDKALTIYAGQRKLLYNAETGEVWDCGAWTADGEREPGGNHWVSTYN
QGTMLGAATLLYLYTKDKMYLEDAKKVYERSRDHLTNNNKIISVCQTVNGDLCGFKGILM
RYVRTYAETFHLEEPLQWMEKNAWHAWQNRNSGGVIWSAWLTKTAESLTRKEGDDEKDVT
NDAFGASTAVSVAFNAHVNRRFAKSVSEGLQPEYFDDIKFAQLTEDPAEGGVTTPVLSGG
WICFRNVDFGQDGISSLDLRLKATKARSYVQVYVDELTDDGLMGRNSGFLTRGDWSDVVV
PLRAGVTGVHDVYIRFNGDGVQSGGIKSTGSGSGVDSPVAVIGEIGSVYNLRGIRVGSSL
DGLPPGIYISGGHKILKR

Enzyme Prediction     

No EC number prediction in MGYG000001666_00410.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	162	469	3e-54	0.8659217877094972

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam03663	Glyco_hydro_76	5.70e-34	171	454	16	320	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
COG4833	COG4833	1.02e-11	186	429	46	280	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].
cd04084	CBM6_xylanase-like	7.78e-11	511	620	4	112	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains. This family includes carbohydrate binding module 6 (CBM6) domains that are appended mainly to glycoside hydrolase (GH) family domains, including GH3, GH11, and GH43 domains. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB6s belonging to this family are Microbispora bispora GghA, a 1,4-beta-D-glucan glucohydrolase (GH3); Clostridium thermocellum xylanase U (GH11), and Penicillium purpurogenum ABF3, a bifunctional alpha-L-arabinofuranosidase/xylobiohydrolase (GH43). GH3 comprises enzymes with activities including beta-glucosidase (hydrolyzes beta-galactosidase) and beta-xylosidase (hydrolyzes 1,4-beta-D-xylosidase). GH11 family comprises enzymes with xylanase (endo-1,4-beta-xylanase) activity which catalyze the hydrolysis of beta-1,4 bonds of xylan, the major component of hemicelluloses, to generate xylooligosaccharides and xylose. GH43 includes beta-xylosidases and beta-xylanases, using aryl-glycosides as substrates. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold.
pfam14200	RicinB_lectin_2	1.03e-06	47	131	1	88	Ricin-type beta-trefoil lectin domain-like.
pfam14200	RicinB_lectin_2	4.75e-05	27	87	28	88	Ricin-type beta-trefoil lectin domain-like.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT74831.1	3.63e-110	7	616	19	633
QIA07414.1	5.92e-76	5	620	59	661
QEC70572.1	6.47e-75	13	501	31	500
AYD48939.1	6.23e-68	27	496	47	495
QOV19890.1	1.76e-54	157	623	29	484

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5M77_A	1.84e-40	187	616	73	506	ChainA, Alpha-1,6-mannanase [Niallia circulans],5M77_B Chain B, Alpha-1,6-mannanase [Niallia circulans]
4BOK_A	1.12e-35	187	467	39	328	ChainA, Alpha-1,6-mannanase [Niallia circulans]
4BOJ_A	1.19e-35	187	467	42	331	ChainA, Alpha-1,6-mannanase [Niallia circulans],4BOJ_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4BOJ_C Chain C, Alpha-1,6-mannanase [Niallia circulans]
4D4A_A	5.99e-35	187	467	60	349	ChainA, Alpha-1,6-mannanase [Niallia circulans],4D4A_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4B_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4B_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4C_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4C_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4D_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4D_B Chain B, Alpha-1,6-mannanase [Niallia circulans],5N0F_A Chain A, Alpha-1,6-mannanase [Niallia circulans],5N0F_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBX_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBX_B Chain B, Alpha-1,6-mannanase [Niallia circulans],7NL5_A Chain A, Alpha-1,6-mannanase [Niallia circulans]
5AGD_A	2.81e-34	187	467	60	349	ChainA, Alpha-1,6-mannanase [Niallia circulans],5AGD_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBM_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_B Chain B, Alpha-1,6-mannanase [Niallia circulans]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.916683	0.082861	0.000165	0.000140	0.000064	0.000108

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001666_00410.