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CAZyme Information: MGYG000001668_01065

You are here: Home > Sequence: MGYG000001668_01065

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA1259 sp900760875
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; Borkfalkiaceae; UBA1259; UBA1259 sp900760875
CAZyme ID MGYG000001668_01065
CAZy Family GT4
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
348 39349.01 9.228
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001668 1885348 MAG United States North America
Gene Location Start: 436;  End: 1482  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001668_01065.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT4 174 307 1e-25 0.8625

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03809 GT4_MtfB-like 1.48e-49 2 327 1 347
glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
cd03801 GT4_PimA-like 1.48e-30 84 323 99 339
phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
pfam00534 Glycos_transf_1 3.24e-26 175 329 1 158
Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
COG0438 RfaB 5.37e-25 90 329 109 358
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
pfam13692 Glyco_trans_1_4 1.75e-18 177 308 2 133
Glycosyl transferases group 1.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ASF42307.1 1.10e-67 1 338 1 343
QLF50143.1 2.19e-67 1 338 1 343
ATA84864.1 1.92e-65 1 338 1 343
QTQ14082.1 7.34e-62 1 338 1 365
QTQ11764.1 1.46e-61 1 338 1 365

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2BFW_A 7.92e-13 178 331 38 198
Structureof the C domain of glycogen synthase from Pyrococcus abyssi [Pyrococcus abyssi]
6ME2_A 2.54e-12 178 336 243 408
XFELcrystal structure of human melatonin receptor MT1 in complex with ramelteon [Homo sapiens]
6ME3_A 2.54e-12 178 336 243 408
XFELcrystal structure of human melatonin receptor MT1 in complex with 2-phenylmelatonin [Homo sapiens],6ME4_A XFEL crystal structure of human melatonin receptor MT1 in complex with 2-iodomelatonin [Homo sapiens],6ME5_A XFEL crystal structure of human melatonin receptor MT1 in complex with agomelatine [Homo sapiens],6PS8_A XFEL MT1R structure by ligand exchange from agomelatine to 2-phenylmelatonin. [Homo sapiens]
3L01_A 5.23e-12 178 331 253 413
ChainA, GlgA glycogen synthase [Pyrococcus abyssi],3L01_B Chain B, GlgA glycogen synthase [Pyrococcus abyssi]
3FRO_A 5.37e-12 178 331 253 413
Crystalstructure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi],3FRO_B Crystal structure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi],3FRO_C Crystal structure of Pyrococcus abyssi glycogen synthase with open and closed conformations [Pyrococcus abyssi]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P26402 6.22e-13 114 314 121 323
Protein RfbU OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfbU PE=3 SV=1
Q59002 1.14e-07 173 286 205 321
Uncharacterized glycosyltransferase MJ1607 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ1607 PE=3 SV=1
Q48453 4.40e-07 170 286 186 297
Uncharacterized 41.2 kDa protein in cps region OS=Klebsiella pneumoniae OX=573 PE=4 SV=1
Q914J0 9.49e-06 234 293 204 263
Putative glycosyltransferase 41 OS=Sulfolobus islandicus filamentous virus (isolate Iceland/Hveragerdi) OX=654908 GN=SIFV0041 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000032 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001668_01065.