dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000001672_00683

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Basic Information help

Species

UMGS995 sp900547465

Lineage

Bacteria; Firmicutes; Bacilli; RF39; UBA660; UMGS995; UMGS995 sp900547465

CAZyme ID

MGYG000001672_00683

CAZy Family

CE3

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
892		101902.57	5.1949

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001672	1285890	MAG	United States	North America

Gene Location

Start: 41029; End: 43707 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000001672_00683.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH25	701	880	1.6e-27	0.9887005649717514
CE3	219	363	1.2e-16	0.6958762886597938

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06414	GH25_LytC-like	3.42e-40	701	891	5	191	The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
cd01841	NnaC_like	3.15e-36	193	369	1	174	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases. E. coli NnaC appears to be involved in polysaccharide synthesis.
cd01828	sialate_O-acetylesterase_like2	1.12e-32	197	370	4	169	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.
pfam13472	Lipase_GDSL_2	1.58e-25	197	360	1	176	GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.
cd06523	GH25_PlyB-like	1.27e-18	699	888	2	175	PlyB is a bacteriophage endolysin that displays potent lytic activity toward Bacillus anthracis. PlyB has an N-terminal glycosyl hydrolase family 25 (GH25) catalytic domain and a C-terminal bacterial SH3-like domain, SH3b. Both domains are required for effective catalytic activity. Endolysins are produced by bacteriophages at the end of their life cycle and participate in lysing the bacterial cell in order to release the newly formed progeny. Endolysins (also referred to as endo-N-acetylmuramidases or peptidoglycan hydrolases) degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJA04626.1	2.63e-28	695	890	108	313
QQR24886.1	4.67e-28	695	890	108	313
ANU71242.1	4.67e-28	695	890	108	313
QIX10955.1	4.67e-28	695	890	108	313
ASU20273.1	4.67e-28	695	890	108	313

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2WW5_A	8.16e-28	680	891	251	468	3D-structureof the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution [Streptococcus pneumoniae R6],2WWD_A 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment [Streptococcus pneumoniae R6]
2WWC_A	1.96e-27	680	891	251	468	3D-structureof the modular autolysin LytC from Streptococcus pneumoniae in complex with synthetic peptidoglycan ligand [Streptococcus pneumoniae R6]
2HSJ_A	2.13e-19	178	369	20	213	Thestructure of a putative platelet activating factor from Streptococcus pneumonia. [Streptococcus pneumoniae TIGR4],2HSJ_B The structure of a putative platelet activating factor from Streptococcus pneumonia. [Streptococcus pneumoniae TIGR4],2HSJ_C The structure of a putative platelet activating factor from Streptococcus pneumonia. [Streptococcus pneumoniae TIGR4],2HSJ_D The structure of a putative platelet activating factor from Streptococcus pneumonia. [Streptococcus pneumoniae TIGR4]
6XPM_A	6.28e-16	197	370	30	202	ChainA, Lysophospholipase L1 [Phocaeicola vulgatus]
6NJC_A	2.89e-15	197	370	30	202	ChainA, Sialate O-acetylesterase [Phocaeicola vulgatus ATCC 8482],6NJC_B Chain B, Sialate O-acetylesterase [Phocaeicola vulgatus ATCC 8482],6XPG_A Chain A, Lysophospholipase L1 [Phocaeicola vulgatus]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P13266	8.19e-08	196	366	253	419	N-acylneuraminate cytidylyltransferase OS=Escherichia coli OX=562 GN=neuA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000260	0.999092	0.000183	0.000144	0.000137	0.000130

TMHMM Annotations help

There is no transmembrane helices in MGYG000001672_00683.