CAZyme Information: MGYG000001674_00142

Basic Information

• Species: UMGS1795 sp900761165
• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-552; UMGS1795; UMGS1795 sp900761165
• CAZyme ID: MGYG000001674_00142
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1470	MGYG000001674_7|CGC1	163986.71	4.2606

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001674	1412802	MAG	United States	North America

• Gene Location: Start: 17152; End: 21564 Strand: +

Full Sequence      

MKKGKFSKITLTFTLVAAMLLGCAAACSGPQNSAVRNGDFSLINGNRAAVIVVEGENTPH
VAEEDEEYPGVTRAAYDLQSDVEKITGKKPVVTSRLSGKTDYAVIVGTLGRSTLIDAVVS
AGKIDVTPIEGKWESYIVQNVTDPFGDGSVKNALVVAGSDKRGSIYGVYSISDMLGMTPW
EFFCDSVPRHRDNLVVPEGYISIGEEPDVKYRGIFINDEETLEAWARVMDDGKHLGPNLY
EKIFEMLLRIKANYLWPGMHACSDAFSDYAENPVNADYYGIVIGTSHCDMLLRNNLNEWE
SFVSEYAKSHGMKEDDIEYDYTVNPEIIREYWRISVRENKDYEVQWTLGMRGAHDEPFTT
ANIDQAPWYGDKNMLMEQIIEDQRQILREELDNPTLEDVFMMFIPYKEVQTLYNDGLVVP
EDVTIMWADDNHGFIRNLPDEQERARSGGLGVYYHNSYWGPDNESYMWVNSMPFTMIYEE
MSKAYAYDIDRAWILNAGDMIPNMPEIEFFVDLGCRISEYSPERVYETYFGKMASREFGE
QFADDVTEIAKRYTLLTNARKIEQMSVDIFSAAYGDESEKRAAAYKELYDLAESVYAAIP
EQSRDCFYETILSEVRNAYYTNAEFYYAHKSNVAYAQGRMSTANNAYNLSLEFNRMRKDE
ISYYNNILSGGKWKNLMDPEIYHSPVMAGFASSSPVFKAGAPEMDAVVEGEGALYSTLAF
GNYARGRKYIDIFNKGSGEISFTISADKDFVVLDKTQGTVSDEARVWVSIDWDKISATET
AVITIKSGDKQKKINVIAVYENYDLPEKTYVDQDGYVSMEAEHWTRAKSTSVAGWKTIKD
LGRVSGDMVRAETQTLVGYDIRSYIDNAPYLEYDAYFASAGDFTTEIYRLPTLNSLGNVR
FAIAVGDGQPIVVEGEKDYGTNNAAWEEGVFTQIIKHEVTLTIPQTGINTVRIYMIDPFI
TIDKIVIYTGEKQQSYFGPDESYNSTYNTTPWVNSEYEAFYEAGKYTLPENYDIAVKYGT
GSFVEEGGAIAIEAESAALGGEGARTEGRWIAARTDAGISMRTADLREDFDGRWTTQAPA
MYYDIVVTSPGDYRVWVNINAPAPRSSTYAIGLDGAHKFTKSDFNWSREEVFLWRDSGST
IYLSEGRHTLIFYCSQDGLAVDKIYLTKNGDTPANNGFVQSARSPLTNMSSEQISSDAAL
RKRLYVAAASAEGIDAIIPGAGPGDYGATALEALKTAAEDAYFLMNSDEALTEAEVSAAE
SAVLNALSALTASRTMSENGTDYLVYETYENYICGFTPYGCELLDVNLSPDIRVAGGEGE
DAYLNIRTFKEQSAVETAYVGYRFGAASALITLETVMSFNEADWGSLYLLNGNGENAVCI
AFEYVYGEYSIVAYNGGVKTKISSYERNVPVSVKIEADISGNTFDVYINGELAAEDFAFR
TDSTELTSVKAGSSARDADLRIYEIKVYGE

Enzyme Prediction     

No EC number prediction in MGYG000001674_00142.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	50	682	2.2e-186	0.8220946915351507

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	7.45e-131	206	563	2	333	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	3.63e-50	809	981	1	172	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	2.43e-05	48	169	21	118	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASA21655.1	5.81e-259	9	1452	11	1481
QGH34463.1	1.92e-203	67	1171	25	1210
QUC63565.1	1.58e-202	39	999	27	964
AFO77172.1	7.72e-201	16	991	28	982
ADJ45460.1	7.72e-201	16	991	28	982

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZMH_A	1.48e-133	50	982	14	933	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	1.96e-96	63	983	24	964	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]
4C90_A	4.16e-85	51	982	46	849	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
5BY3_A	4.42e-83	39	678	19	616	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
7PUG_A	1.02e-82	51	677	19	625	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000001	0.000036	1.000029	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
13	35