logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001698_02420

You are here: Home > Sequence: MGYG000001698_02420

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Marvinbryantia formatexigens
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Marvinbryantia; Marvinbryantia formatexigens
CAZyme ID MGYG000001698_02420
CAZy Family GH129
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
631 MGYG000001698_12|CGC1 72600 4.9894
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001698 4516105 Isolate United States North America
Gene Location Start: 18672;  End: 20567  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.49

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH129 4 630 3e-212 0.9514563106796117

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14244 GH_101_like 1.90e-109 284 566 3 290
Endo-a-N-acetylgalactosaminidase and related glcyosyl hydrolases. This family contains the enzymatically active domain of cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins (EC:3.2.1.97). It has been classified as glycosyl hydrolase family 101 in the Cazy resource. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae and other commensal human bacteria is largely determined by their ability to degrade host glycoproteins and to metabolize the resultant carbohydrates.
pfam18952 DUF5696 2.39e-12 169 427 126 400
Family of unknown function (DUF5696). This is a family of unknown function with some overlap with clan family members of CL0058.
pfam12905 Glyco_hydro_101 6.57e-12 313 437 47 178
Endo-alpha-N-acetylgalactosaminidase. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae is largely determined by the ability to degrade host glycoproteins and to metabolize the resultant carbohydrates. This family is the enzymatic region, EC:3.2.1.97, of the cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins. This reaction is exemplified by the S. pneumoniae protein Endo-alpha-N-acetylgalactosaminidase, where Asp764 is the catalytic nucleophile-base and Glu796 the catalytic proton donor.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUO33311.1 3.49e-309 1 628 1 627
QBF72900.1 1.20e-307 1 629 1 628
QRO36270.1 1.20e-307 1 629 1 628
AHJ19301.1 2.50e-281 11 630 10 627
ALE13276.1 3.54e-281 11 630 10 627

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5WZN_A 1.17e-268 1 628 1 628
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZN_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZP_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZP_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZR_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum],5WZR_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum]
5WZQ_A 6.84e-263 1 628 1 628
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum],5WZQ_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum]
6QEP_A 6.63e-08 320 436 340 458
EngBFDARPin Fusion 4b H14 [Bifidobacterium longum]
6QEV_B 6.64e-08 320 436 340 458
EngBFDARPin Fusion 4b B6 [Bifidobacterium longum]
6QFK_A 6.64e-08 320 436 340 458
EngBFDARPin Fusion 4b G10 [Bifidobacterium longum]

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000044 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001698_02420.