CAZyme Information: MGYG000001698_03487

Basic Information

• Species: Marvinbryantia formatexigens
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Marvinbryantia; Marvinbryantia formatexigens
• CAZyme ID: MGYG000001698_03487
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1205	MGYG000001698_23|CGC1	135199.37	4.8524

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001698	4516105	Isolate	United States	North America

• Gene Location: Start: 54326; End: 57943 Strand: -

Full Sequence      

MLFNDGWEFSRQPLHTTFSEMKEREQMFSPVGLPHDWLIYDTNHLYEDGTGWYRKRFVLE
KKEQELVFLRFDGIYMDSRVYVNGHLAGEWKYGYSAFELDITPFLEDGENEIRVSVDFQA
PNSRWYSGAGIYRNVWLKQVPREHLVSDGIYFHAEPVKAAPENDWNIDLEVETTGCDLTV
TADLLAEDGTLLPVRQGTGNAGEKEGQQGTWSIQPKEGQTGVWVHSIRLLAERPKLWDVE
SPNLYTLRVRLFKDGVLLQTEEQRVGFRAIAYLPDGGFFLNGRHIKLNGVCEHHDLGCLG
SAFHEQAMRRKFEIIKNMGANAVRFAHNMPAAEAMDLADEMGLLVISEAFDMWESAKTPY
DYARFFQQWYQRDVASWIRRDRNHPSVIMWCVGNEIHDTHAGEKGRLWMERLMAEVEKHD
AKHNAPPTLASNYMPWENTQKCADVIKLIGYNYGEKYYDSHHAQHPDWIIYGSETSSVVQ
SRGIYHFPYKQSVLADDDEQCSALGNSTTSWGAKSAEACVIAERDRPYSCGQFLWSGFDY
IGEPTPYHTRNSYFGQIDTAGFPKDPYYLYQAEWNDLRKKTVLHLFPYWDFNEGQLVDVR
AYTNAPEVELFLNGKSCGVCRIDHAHGTTLSGNWQVPYEKGEIRAIARDENGNVLAEDAR
HSFGEAAHIMLTPEQETLRADGHDLLFLQISMTDADGYPVENANNRVQVTVTGAGALAGC
DNGDSTETDGYKTGSRRLFGGKLLAVIKAGTQAGELCVTVSSPGLPEAHLTLQVRESAAV
RGSSPEAYLAEMPVRKAAENSLPADADATSFRNALPADAGATPSEVPSAGEAAAKMTGER
DGSEEQKNTEIPVRNIRLMSSAGNHLSEEVPETTVTAQLCPDNADDKEVIWRIVDDAGIP
SPLAELQADGRTAHVRAKSDGCFRLRCMSRCGTEKVRIISQMEFTVTGLGKAFLDPYSFV
SGGLYNYSRGDVGNGNEHGVATARDGETQVGFRELDFGPDGSDEICLPIFALTDEPYEIK
IYEGMPGEPGAELIADVIYQKPSIWNTYQEETYRLNKWLRGITGICFVLQKKIHLKGFSF
VKKNRAFEKLAAVQCDAIYGDSFRIADGVVREIGNNVTLEFGGLDFGQEGAARITICGST
PHEKNTIVLRFASEAGEETRMLEFMRGEPVQTFSFERICGRQTVRFVFLPGSCFDFDWIQ
FERES

Enzyme Prediction     

EC	3.2.1.23

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	579	3.2e-110	0.6103723404255319

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.26e-67	36	590	64	614	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	4.49e-46	49	458	65	473	beta-D-glucuronidase; Provisional
pfam18565	Glyco_hydro2_C5	5.17e-38	669	771	1	103	Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.
PRK10340	ebgA	1.27e-32	47	395	107	449	cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525	lacZ	3.13e-32	47	395	118	462	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJU15650.1	0.0	1	1205	1	1148
ASU31293.1	0.0	1	1205	1	1148
ANU74303.1	0.0	1	1205	1	1148
QQQ91838.1	0.0	1	1205	1	1148
AGA58497.1	0.0	1	1203	5	1141

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7CWD_A	1.66e-167	3	778	6	805	ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
4YPJ_A	8.34e-166	3	765	12	798	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
4CU6_A	2.00e-152	3	772	18	842	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU7_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU8_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4]
4CUC_A	5.49e-152	3	772	18	842	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA. [Streptococcus pneumoniae TIGR4]
5T98_A	2.08e-142	3	774	30	820	Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	2.56e-161	31	776	74	850	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09	2.28e-90	3	762	51	808	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KPJ7	7.05e-59	31	647	82	702	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P77989	3.02e-40	3	719	8	695	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KN75	2.28e-36	3	773	31	794	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000064	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001698_03487.