CAZyme Information: MGYG000001700_02855

Basic Information

• Species: Citrobacter_A sedlakii
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Citrobacter_A; Citrobacter_A sedlakii
• CAZyme ID: MGYG000001700_02855
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
382		42451.49	7.464

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001700	4631466	Isolate	not provided	not provided

• Gene Location: Start: 18073; End: 19221 Strand: -

Full Sequence      

MAEQRPLTIALVAGETSGDILGAGLIRALKARVPHARFVGVAGPRMQAEGCEAWYEMEEL
AVMGIVEVLGRLRRLLHIRADLTRRFTGLKPDVFVGIDAPDFNITLEGNLKKQGIKTIHY
VSPSVWAWRQKRVFKIGRSTNMVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNA
ARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQRLRQHYPDLEVVVPLVNAKRREQ
FEKIKADVAPELSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTF
WLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAQALLPLLANGETSHAMHDTFRE
LHQQIRCNADEQAADAVLELAQ

Enzyme Prediction     

No EC number prediction in MGYG000001700_02855.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	9	366	4.8e-142	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
TIGR00215	lpxB	0.0	1	380	1	385	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
COG0763	LpxB	0.0	6	382	1	380	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
PRK00025	lpxB	0.0	6	382	1	376	lipid-A-disaccharide synthase; Reviewed
pfam02684	LpxB	0.0	9	377	1	374	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK01021	lpxB	3.80e-47	11	328	231	551	lipid-A-disaccharide synthase; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUC29285.1	4.47e-277	1	382	1	382
AST78556.1	6.52e-270	1	381	1	381
ALD76594.1	1.87e-269	1	382	1	382
QGS13447.1	1.87e-269	1	382	1	382
QRQ73174.1	1.87e-269	1	382	1	382

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8N_A	6.42e-260	1	382	1	382	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A	5.27e-259	1	382	1	382	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A9MPH9	8.80e-269	1	382	1	382	Lipid-A-disaccharide synthase OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) OX=41514 GN=lpxB PE=3 SV=1
B4TK57	2.52e-268	1	382	1	382	Lipid-A-disaccharide synthase OS=Salmonella heidelberg (strain SL476) OX=454169 GN=lpxB PE=3 SV=1
B4SV11	2.52e-268	1	382	1	382	Lipid-A-disaccharide synthase OS=Salmonella newport (strain SL254) OX=423368 GN=lpxB PE=3 SV=1
B4TYE2	2.52e-268	1	382	1	382	Lipid-A-disaccharide synthase OS=Salmonella schwarzengrund (strain CVM19633) OX=439843 GN=lpxB PE=3 SV=1
B5RHG7	2.52e-268	1	382	1	382	Lipid-A-disaccharide synthase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000064	0.000003	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001700_02855.