CAZyme Information: MGYG000001708_01087

Basic Information

• Species: Providencia rustigianii
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Providencia; Providencia rustigianii
• CAZyme ID: MGYG000001708_01087
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
383		42542.62	7.3083

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001708	3896203	Isolate	not provided	not provided

• Gene Location: Start: 147945; End: 149096 Strand: +

Full Sequence      

MNSNRPLTIGLVAGETSGDILGAGLIRALKQQVPNARFVGVAGPLMQAEGCEAWYEMEEL
AVMGIVEVLGRLPRLLSIRKDLTQRFTELQPDVFVGIDAPDFNITLEGKLKSTGIKTIHY
VSPSVWAWRQKRVFKIGRSTNLVLAFLPFEKAFYDRFDVPCRFIGHTMADAIALNPDKQA
ARERLNIPATSKCLALLPGSRHSEVEMLSADFLKTATLLSNHFTDLQIVVPLVNQKRRQQ
FDEIKQQVAPELNVHILDGQARDAMMAADATLLASGTAALECMLTKCPMVVGYRMKPFTF
WLAKRLVKTPYVSLPNLLAGKEIVKELLQDECQPEQLAAQLLPLLEGGEQVDALKQTFLQ
LHQLIRCDADKQAADAVLDLVRN

Enzyme Prediction     

No EC number prediction in MGYG000001708_01087.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	9	366	2.4e-141	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00025	lpxB	0.0	6	383	1	377	lipid-A-disaccharide synthase; Reviewed
COG0763	LpxB	2.06e-180	6	382	1	380	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
TIGR00215	lpxB	4.60e-180	1	380	1	385	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
pfam02684	LpxB	9.69e-167	9	377	1	374	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK01021	lpxB	3.79e-52	11	328	231	551	lipid-A-disaccharide synthase; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
VEH56414.1	1.14e-275	1	383	1	383
QLR04150.1	1.58e-264	1	382	2	383
ATG16379.1	1.84e-263	1	382	2	383
SQI40501.1	1.84e-263	1	382	2	383
QLQ96764.1	1.84e-263	1	382	2	383

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8N_A	7.38e-211	1	382	1	382	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A	6.04e-210	1	382	1	382	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q7N8N4	8.51e-223	1	380	7	386	Lipid-A-disaccharide synthase OS=Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265 GN=lpxB PE=3 SV=1
Q667K2	1.38e-220	1	380	12	391	Lipid-A-disaccharide synthase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) OX=273123 GN=lpxB PE=3 SV=1
Q8ZH55	1.38e-220	1	380	12	391	Lipid-A-disaccharide synthase OS=Yersinia pestis OX=632 GN=lpxB PE=3 SV=1
C6DAJ6	7.57e-220	3	382	2	381	Lipid-A-disaccharide synthase OS=Pectobacterium carotovorum subsp. carotovorum (strain PC1) OX=561230 GN=lpxB PE=3 SV=1
A8GID3	6.96e-218	4	382	3	381	Lipid-A-disaccharide synthase OS=Serratia proteamaculans (strain 568) OX=399741 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000048	0.000006	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001708_01087.