CAZyme Information: MGYG000001746_01293

Basic Information

• Species: CAG-273 sp900752095
• Lineage: Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-273; CAG-273 sp900752095
• CAZyme ID: MGYG000001746_01293
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
740		88366.27	9.6972

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001746	1549413	MAG	Sweden	Europe

• Gene Location: Start: 278; End: 2500 Strand: +

Full Sequence      

MTNQYKISTIIPVYNVEPYLEETIKSIIHQTIGFKKNIQLILINDGSTDKSETICLKYKK
QYPENILYVAKKNEGVSVARNLGLQFARGNYINFLDSDDYLDLDFYQKAYQMLEENKQID
LVAARLKYFEASEKYHWLDYKFTSDRIIDIKKEPESILLHMSTALIRAQVIKKLKFDPNL
KVSEDTKLLYEIILQKEKYGILASSIYHYRKRKDGSSAIQTSNNKRDWYTDTIKYCHDYL
IKLSMQKYGVVIPYVQHFIMYNLQWRIKTKIADSLTEKEKINYVNTMKKHLSIIDDNIIL
FQKQMKNSYKLLALKVKYGKKLEQYLKSGEDGIYFKEQLFIPYNSITNNVQLAHIEKGKL
IVEGNIILYNFPLYYTINGEKRVEINTYLKNTIDSIFEPEYDVEKYGYLAEIPLENVHSL
EFQIKVGENFYTIKNKFLHFSRINNFKAGYYYDEKYLITKKNNLQLQVECNPLALKVFGK
ELYFLGYIILKRKQLKIAFMRMLYWLTKPFMPKNIWLFSDREFMGRDSGELLFRYTNKQP
QETKRNTYFLLDKHYEDYNRMKQYGKVISYHTMKYRLFFLNAKYIISSHADSYVNNAFGK
ARKYYVDLFHFEYIYLTHGILLHDSSAWLNRINKNIALNVVTSQIEYEALLDGSYYFKPE
QLMKTGLPRHDNLMQQDIKEENKILIMASWRSSLAGCVIPGTQRRAYNPKFKKSEYFQFY
DRLFQDKRLIETLQKYRLQN

Enzyme Prediction     

No EC number prediction in MGYG000001746_01293.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	8	173	1.4e-30	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd00761	Glyco_tranf_GTA_type	7.10e-23	10	92	2	81	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	4.94e-21	8	92	1	82	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
PRK10073	PRK10073	3.24e-20	1	116	2	113	putative glycosyl transferase; Provisional
COG0463	WcaA	5.53e-16	3	94	1	89	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd06433	GT_2_WfgS_like	1.59e-14	8	210	1	194	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASB95121.1	7.55e-147	3	735	5	749
AYE66140.1	8.97e-144	5	735	8	753
AQR87819.1	8.97e-144	5	735	8	753
BBK74332.1	8.97e-144	5	735	8	753
AMB25812.1	8.97e-144	5	735	8	753

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HEA_A	9.40e-26	1	217	1	223	CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]
3BCV_A	9.05e-22	6	210	6	225	Crystalstructure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3BCV_B Crystal structure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]
5TZE_C	4.35e-14	6	229	2	222	Crystalstructure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZE_E Crystal structure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZI_C Crystal structure of S. aureus TarS 1-349 [Staphylococcus aureus],5TZJ_A Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZJ_C Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZK_C Crystal structure of S. aureus TarS 1-349 in complex with UDP [Staphylococcus aureus]
5TZ8_A	1.04e-13	6	229	2	222	Crystalstructure of S. aureus TarS [Staphylococcus aureus],5TZ8_B Crystal structure of S. aureus TarS [Staphylococcus aureus],5TZ8_C Crystal structure of S. aureus TarS [Staphylococcus aureus]
6P61_A	6.64e-13	7	160	15	174	Structureof a Glycosyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) [Leptospira borgpetersenii serovar Hardjo-bovis str. JB197],6P61_B Structure of a Glycosyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) [Leptospira borgpetersenii serovar Hardjo-bovis str. JB197],6P61_C Structure of a Glycosyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) [Leptospira borgpetersenii serovar Hardjo-bovis str. JB197],6P61_D Structure of a Glycosyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) [Leptospira borgpetersenii serovar Hardjo-bovis str. JB197]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P46918	1.79e-144	5	735	8	753	Minor teichoic acid biosynthesis protein GgaB OS=Bacillus subtilis (strain 168) OX=224308 GN=ggaB PE=3 SV=1
P46917	3.83e-46	8	448	3	437	Minor teichoic acid biosynthesis protein GgaA OS=Bacillus subtilis (strain 168) OX=224308 GN=ggaA PE=3 SV=1
A0A0H2URH7	8.59e-28	6	279	6	283	Glycosyltransferase GlyA OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=glyA PE=3 SV=1
P71059	5.59e-24	7	219	5	221	Uncharacterized glycosyltransferase EpsJ OS=Bacillus subtilis (strain 168) OX=224308 GN=epsJ PE=2 SV=1
Q57022	3.19e-19	3	270	2	249	Uncharacterized glycosyltransferase HI_0868 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_0868 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000065	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001746_01293.