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CAZyme Information: MGYG000001750_01536

You are here: Home > Sequence: MGYG000001750_01536

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola ilei
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola ilei
CAZyme ID MGYG000001750_01536
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
280 33770.18 9.4989
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001750 2839699 MAG Sweden Europe
Gene Location Start: 3372;  End: 4214  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001750_01536.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 3 276 1.5e-74 0.9855072463768116

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.77e-62 1 258 1 252
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 4.17e-32 4 275 4 295
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.
cd11296 O-FucT_like 0.008 116 242 44 196
GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QQY37044.1 7.16e-145 1 279 1 280
QUT58051.1 7.16e-145 1 279 1 280
ABR40839.1 7.16e-145 1 279 1 280
QEW36700.1 7.16e-145 1 279 1 280
QQY44012.1 7.16e-145 1 279 1 280

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 5.19e-27 6 275 5 300
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1
P19526 8.31e-18 79 246 143 317
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=FUT1 PE=1 SV=1
Q9TUD6 8.38e-18 79 246 144 318
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Pan troglodytes OX=9598 GN=FUT1 PE=3 SV=1
Q9TUD4 5.44e-17 96 246 161 318
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Gorilla gorilla gorilla OX=9595 GN=FUT1 PE=3 SV=1
Q866C5 5.44e-17 79 246 144 318
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Plecturocebus brunneus OX=1812042 GN=FUT1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000045 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001750_01536.