CAZyme Information: MGYG000001776_00185

Basic Information

• Species: UBA3789 sp900543055
• Lineage: Bacteria; Firmicutes; Bacilli; RF39; UBA660; UBA3789; UBA3789 sp900543055
• CAZyme ID: MGYG000001776_00185
• CAZy Family: GT51
• CAZyme Description: Penicillin-binding protein 1A/1B

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
903		99556.51	9.3125

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001776	1642910	MAG	Denmark	Europe

• Gene Location: Start: 37806; End: 40517 Strand: +

Full Sequence      

MQKKVIKRKKSPNTRSKSKSKNTNNSIKIAILLAGVAIILLTYMTLGIELTILMAILLAI
VYGVWHLLQKIQSKTKKRKVVSILLIIFFGFGITCLVGFSAFMIYVKAKADPLFDTANLN
TVELTRLYDKDGKEFAKLGSEKREKVSYEQLPEVLIDAIVATEDSRFFQHNGFDAPRFLK
AALGQLAGHSGAGGASTLSMQVVKNSFTDHLGQKTAGKDGIVRKFEDIYLAVFKLEKKYS
KEEIIEYYVNNHFLGGNIYGVQEAAKTYFGKDVSELNLSEAATIAGMFKSPNYYRPNVNP
KNATARRQTVLNLMVRHGYITKEEADIAAAIPMDSLTTTDSSSGILSQYQGYIDTIADEI
TDKYGINPYTTPLLVYTNLDRSRQDAVNSVLNGENYNWINNKVQTGVAVLDSETGKILAI
GNGRNVNNRSNDNVDQYNYATQIKRQPGSTAKPLFDYGPGIEYNNWSTYELFDDAPYGYS
NGRSIKNWDGKYFGTITLRRALSTSRNIPALKAFQKVDNKKIRKFVTSLGITPEVCNSGY
KYDKEKDLCINKTDSSDTQNPLTLHEAHSIGAFTGVSPLEMSAAYAAFSNGGYYNEPYTV
EKIVFRQTKKEVTHKSTKTQVMSDATAFMISSVLQDVSLTGGTPKNVACKTGTTNFDDNT
MKNYRMPNDAIRDSWVVGYSTKTVIGMWYGYDSFTKQSIADGYVLHNVPATIQKDRLFNA
LVSAGAMESNREEFKQPSSVVKVGVAAGSNPAKLASPGQSAIYEYFKKGYEPNEYDTSSY
KLPAPGNLKATESDGRVTLSWSSVNHSSISAISDYGKFGYNIYKDGVLIGWTDKTSYAFT
PDGSVYGNYKIVATFKSYSGITSEAATITLKESSKPSPSSAPSEDPSPSPSPSPSEDTIT
PVE

Enzyme Prediction     

No EC number prediction in MGYG000001776_00185.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	131	315	4.2e-58	0.9943502824858758

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	1.22e-149	70	692	2	572	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009	MrcA	3.25e-108	88	776	8	768	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912	Transgly	1.99e-72	131	315	1	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG4953	PbpC	1.96e-68	95	690	9	534	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
PRK11636	mrcA	2.79e-46	79	775	2	831	penicillin-binding protein 1a; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AWI12666.1	2.75e-155	69	874	16	780
AXM90108.1	2.85e-150	72	802	23	716
AKS38635.1	2.85e-150	72	802	23	716
ACJ33515.1	2.85e-150	72	802	23	716
APH04640.1	5.25e-150	89	813	40	724

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3DWK_A	1.15e-79	126	759	9	615	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A	1.44e-76	112	759	4	624	StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3ZG8_B	1.01e-52	234	697	2	438	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B	1.37e-48	234	697	2	438	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
3UDF_A	3.10e-44	126	695	22	692	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39793	2.97e-135	73	802	23	728	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q00573	1.21e-93	96	703	26	612	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
Q04707	2.34e-88	72	753	1	653	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59	4.45e-87	72	753	1	653	Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
P38050	1.03e-66	74	692	3	571	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999995	0.000048	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

start	end
25	47
51	68
80	102