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CAZyme Information: MGYG000001780_00278

You are here: Home > Sequence: MGYG000001780_00278

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000001780_00278
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
678 MGYG000001780_2|CGC2 78947.37 7.6386
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001780 6261722 MAG Denmark Europe
Gene Location Start: 38362;  End: 40398  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL12 416 546 8.7e-66 0.9923664122137404

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 0.0 42 395 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 7.41e-38 413 631 9 234
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUT89926.1 0.0 20 678 8 665
ALJ58957.1 0.0 20 678 8 665
AVM56400.1 0.0 29 674 14 661
ADV43619.1 0.0 20 678 8 665
QDO67526.1 0.0 33 678 20 665

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JMD_A 0.0 39 678 16 655
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 0.0 39 678 16 655
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMI_A 6.03e-201 33 674 1 632
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
4MMH_A 8.53e-201 33 674 1 632
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4FNV_A 2.39e-129 40 678 48 702
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C7EXL6 0.0 20 678 8 666
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 7.97e-200 33 674 25 656
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
Q89YR9 1.31e-128 40 678 48 702
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000530 0.998291 0.000661 0.000176 0.000165 0.000153

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001780_00278.