CAZyme Information: MGYG000001789_02014

Basic Information

• Species: Phocaeicola sp002161565
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp002161565
• CAZyme ID: MGYG000001789_02014
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
855	MGYG000001789_36|CGC1	97620.57	5.428

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001789	3544186	MAG	Denmark	Europe

• Gene Location: Start: 7189; End: 9756 Strand: -

Full Sequence      

MKKLSALLGLLLGVLYAYAAEPFITFKKTEGAFPVVGNGQPCTILVDKNENSAILIAVKN
LQEDFLRVTGKKAETVNTPSDGRYILVGSIESPFIKQLFKAGKLNRKDLEGKNEKYVIQT
VDQPLEGVEQALVIAGSDRRGTVYGIYELSRQMGVSPWYWWMDVPVTRQTEVYAQAGVYT
DGEPAVTYRGIFLNDEAPCLTTWVKNTYGTNYGDHRFYARVFELILRLKGNFMWPAMWGW
AFYADDPENSKTADEMGIIMGTSHHEPMARNHQEYARNREKYGAWNYETNAEGLNRFFRE
GIERMKDTEDVVTIGMRGDGDTAMGGEEGKDHEYVPQFERNKRLMETIFKNQRRIIKDVT
GRPAEETPQVWALYKEVLEYYDRGLRVPEDVIMLLCDDNWGNVRRLPNAEERKHPGGWGM
YYHVDYVGAPRNSKWINATPIQNMWEQLQLTYEYGVDKLWVLNVGDLKPMEYPITLFLDM
AWNPQAYNAGTLLQHTYDFCRQAFGDTQAEEAARILNLCCKYNGRSTAEMLDHTVYNLET
GEWRQVVGDYAQLEAEALRQYISLKPEYRDAYKQLILFPVQAMANLHEMYYAQAMNLKLY
AEGNPEANAWADKVEKAFARDKQLCDDYNHVMSGGKWNGMMIQKHIGYTSWNDNFPADKL
PEIHRIGNPEAATGGYLFTGKDGYVAMEAEHYFACTDAGEAKWTVIPYMGRTLSGMSLMP
YTVPANGASLSYKLNIPEKADSVTVHVIVKSTLAFHTPEGHKYNIGFEGGQEETVNFNRD
LNEDPENIYTVYYPTIARRVVEKQVRLKLPVSADGTYTLNFRPLDPGIVLEKIVVDYGGY
QPAYLFGNESPCRRK

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	31	833	4.3e-278	0.9971305595408895

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	182	530	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	9.78e-41	678	845	2	168	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	1.60e-06	45	149	24	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT78586.1	0.0	1	855	1	843
QDM11119.1	0.0	1	855	1	843
ALJ48348.1	0.0	1	855	1	843
EDO10816.1	0.0	1	855	12	854
SCV07757.1	0.0	1	855	12	854

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	1	855	12	854	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	0.0	24	854	7	838	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	0.0	24	854	6	837	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	7.48e-179	23	851	5	934	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	2.08e-121	85	654	65	648	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000234	0.999106	0.000163	0.000163	0.000155	0.000142

TMHMM  Annotations     

start	end
7	26