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CAZyme Information: MGYG000001791_00011
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Verrucomicrobiae; Opitutales; UBA953; W0P29-029; | |||||||||||
| CAZyme ID | MGYG000001791_00011 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipid A biosynthesis lauroyltransferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 11287; End: 13224 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 394 | 621 | 2.9e-36 | 0.8711111111111111 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 4.88e-42 | 315 | 639 | 1 | 275 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 2.04e-41 | 314 | 644 | 2 | 331 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| COG1560 | HtrB | 1.95e-32 | 4 | 284 | 20 | 297 | Lauroyl/myristoyl acyltransferase [Lipid transport and metabolism]. |
| cd07984 | LPLAT_LABLAT-like | 4.54e-25 | 98 | 284 | 12 | 192 | Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins. |
| TIGR02195 | heptsyl_trn_II | 6.98e-25 | 315 | 608 | 1 | 290 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QYY35688.1 | 4.91e-181 | 8 | 643 | 9 | 639 |
| QYM80399.1 | 3.32e-162 | 1 | 630 | 2 | 616 |
| ATC65288.1 | 3.31e-161 | 1 | 644 | 2 | 636 |
| AWT60417.1 | 2.28e-126 | 9 | 643 | 11 | 633 |
| QXD27453.1 | 2.80e-113 | 1 | 644 | 1 | 645 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1PSW_A | 9.73e-13 | 315 | 613 | 2 | 305 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
| 3TOV_A | 2.82e-06 | 314 | 615 | 9 | 306 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P45042 | 4.80e-15 | 321 | 608 | 8 | 300 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| P37692 | 6.57e-15 | 315 | 613 | 2 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 8.80e-15 | 315 | 613 | 2 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| P45239 | 3.15e-06 | 37 | 209 | 58 | 223 | Lipid A biosynthesis lauroyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=lpxL PE=3 SV=2 |
| P24205 | 3.35e-06 | 37 | 202 | 63 | 223 | Lipid A biosynthesis myristoyltransferase OS=Escherichia coli (strain K12) OX=83333 GN=lpxM PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.740077 | 0.256536 | 0.002114 | 0.000545 | 0.000332 | 0.000392 |