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CAZyme Information: MGYG000001807_00012
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; | |||||||||||
| CAZyme ID | MGYG000001807_00012 | |||||||||||
| CAZy Family | CBM51 | |||||||||||
| CAZyme Description | Arylsulfatase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 18169; End: 19755 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16025 | PAS_like | 1.81e-180 | 27 | 476 | 1 | 402 | Bacterial Arylsulfatase of Pseudomonas aeruginosa and related proteins. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases. |
| cd16144 | ARS_like | 8.44e-119 | 29 | 494 | 1 | 421 | uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases. |
| cd16146 | ARS_like | 5.04e-100 | 29 | 494 | 1 | 404 | uncharacterized arylsulfatase. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases. |
| cd16145 | ARS_like | 5.77e-95 | 29 | 481 | 1 | 415 | uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases. |
| cd16029 | 4-S | 3.63e-94 | 29 | 477 | 1 | 393 | N-acetylgalactosamine 4-sulfatase, also called arylsulftase B. Sulfatases catalyze the hydrolysis of sulfuric acid esters from a wide variety of substrates. N-acetylgalactosamine 4-sulfatase catalyzes the removal of the sulfate ester group from position 4 of an N-acetylgalactosamine sugar at the non-reducing terminus of the polysaccharide in the degradative pathways of the glycosaminoglycans dermatan sulfate and chondroitin-4-sulfate. N-acetylgalactosamine 4-sulfatase is a lysosomal enzyme. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QDV62831.1 | 1.08e-106 | 6 | 495 | 3 | 546 |
| QDV47687.1 | 5.14e-105 | 26 | 520 | 648 | 1153 |
| QEF96404.1 | 2.78e-103 | 25 | 520 | 650 | 1156 |
| CAD72594.1 | 3.47e-101 | 14 | 495 | 40 | 567 |
| QDV88366.1 | 4.92e-101 | 26 | 520 | 648 | 1153 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7ALL_AAA | 1.25e-295 | 25 | 526 | 23 | 523 | ChainAAA, Arylsulfatase [Bacteroides thetaiotaomicron VPI-5482] |
| 1HDH_A | 1.48e-78 | 29 | 500 | 5 | 526 | Arylsulfatasefrom Pseudomonas aeruginosa [Pseudomonas aeruginosa],1HDH_B Arylsulfatase from Pseudomonas aeruginosa [Pseudomonas aeruginosa] |
| 4CXK_A | 2.90e-78 | 29 | 500 | 5 | 526 | G9mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa],4CXK_B G9 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa] |
| 4CXS_A | 1.12e-77 | 29 | 500 | 5 | 526 | G4mutant of PAS, arylsulfatase from Pseudomonas aeruginosa, in complex with Phenylphosphonic acid [Pseudomonas aeruginosa],4CXS_B G4 mutant of PAS, arylsulfatase from Pseudomonas aeruginosa, in complex with Phenylphosphonic acid [Pseudomonas aeruginosa],4CXU_A G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with 3-Br-Phenolphenylphosphonate [Pseudomonas aeruginosa],4CXU_B G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa, in complex with 3-Br-Phenolphenylphosphonate [Pseudomonas aeruginosa],4CYR_A G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa],4CYR_B G4 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa] |
| 5AJ9_A | 1.57e-77 | 29 | 500 | 5 | 526 | G7mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa],5AJ9_B G7 mutant of PAS, arylsulfatase from Pseudomonas Aeruginosa [Pseudomonas aeruginosa] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P51691 | 8.08e-78 | 29 | 500 | 5 | 526 | Arylsulfatase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=atsA PE=1 SV=3 |
| Q9X759 | 1.31e-74 | 5 | 507 | 2 | 541 | Arylsulfatase OS=Klebsiella pneumoniae OX=573 GN=atsA PE=1 SV=1 |
| Q9C0V7 | 5.01e-70 | 25 | 516 | 8 | 548 | Uncharacterized sulfatase PB10D8.02c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBPB10D8.02c PE=3 SV=1 |
| P20713 | 5.96e-64 | 5 | 432 | 2 | 452 | Arylsulfatase OS=Klebsiella aerogenes OX=548 GN=atsA PE=1 SV=1 |
| P33727 | 3.94e-46 | 19 | 505 | 37 | 520 | Arylsulfatase B OS=Felis catus OX=9685 GN=ARSB PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000336 | 0.998917 | 0.000197 | 0.000195 | 0.000176 | 0.000156 |