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CAZyme Information: MGYG000001810_00706

You are here: Home > Sequence: MGYG000001810_00706

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mediterraneibacter sp002314255
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter; Mediterraneibacter sp002314255
CAZyme ID MGYG000001810_00706
CAZy Family CBM13
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1561 MGYG000001810_6|CGC1 169030.09 4.3563
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001810 2943094 MAG Denmark Europe
Gene Location Start: 36071;  End: 40756  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001810_00706.

CAZyme Signature Domains help

Family Start End Evalue family coverage
CBM13 947 1088 5.1e-23 0.7074468085106383
CBM13 1244 1334 1e-22 0.4627659574468085
CBM13 659 804 3.1e-21 0.7340425531914894
CBM13 816 937 2e-20 0.6542553191489362
CBM13 510 651 5.7e-20 0.7074468085106383

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02696 MurNAc-LAA 1.79e-24 292 494 1 172
N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.
pfam14200 RicinB_lectin_2 3.35e-24 1279 1365 2 89
Ricin-type beta-trefoil lectin domain-like.
pfam14200 RicinB_lectin_2 1.61e-22 694 778 1 86
Ricin-type beta-trefoil lectin domain-like.
pfam14200 RicinB_lectin_2 6.59e-22 984 1070 1 88
Ricin-type beta-trefoil lectin domain-like.
pfam14200 RicinB_lectin_2 1.42e-21 1224 1319 1 89
Ricin-type beta-trefoil lectin domain-like.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRT50579.1 1.30e-240 138 1558 119 1696
VCV20908.1 3.75e-97 123 1553 170 1459
CBL07763.1 1.21e-95 123 1553 164 1453
CBL13779.1 2.20e-95 123 1553 165 1454
QEI32622.1 2.19e-82 123 1553 67 1305

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5J72_A 1.69e-07 265 493 429 633
ChainA, Putative N-acetylmuramoyl-L-alanine amidase,autolysin cwp6 [Clostridioides difficile 630],5J72_B Chain B, Putative N-acetylmuramoyl-L-alanine amidase,autolysin cwp6 [Clostridioides difficile 630]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O51481 2.77e-21 1418 1518 68 168
Uncharacterized protein BB_0531 OS=Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326 GN=BB_0531 PE=3 SV=1
O48471 1.45e-09 292 501 4 185
Endolysin OS=Bacillus phage SPP1 OX=10724 GN=25 PE=4 SV=1
P37134 3.16e-07 291 501 2 179
N-acetylmuramoyl-L-alanine amidase CwlM OS=Bacillus licheniformis OX=1402 GN=cwlM PE=3 SV=1
P54525 5.57e-07 293 496 32 203
Uncharacterized protein YqiI OS=Bacillus subtilis (strain 168) OX=224308 GN=yqiI PE=3 SV=3

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.013146 0.985519 0.000595 0.000239 0.000236 0.000242

TMHMM  Annotations      download full data without filtering help

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