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CAZyme Information: MGYG000001861_01002
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; HGM13634; | |||||||||||
| CAZyme ID | MGYG000001861_01002 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1566; End: 2387 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 4 | 269 | 2.2e-57 | 0.9818840579710145 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 1.19e-56 | 1 | 255 | 1 | 257 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 8.56e-24 | 122 | 270 | 150 | 297 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ALK86002.1 | 1.37e-198 | 10 | 273 | 1 | 264 |
| QUT29887.1 | 1.41e-143 | 1 | 273 | 1 | 274 |
| QRN01080.1 | 1.41e-143 | 1 | 273 | 1 | 274 |
| QUT24461.1 | 1.41e-143 | 1 | 273 | 1 | 274 |
| CBK69212.1 | 1.41e-143 | 1 | 273 | 1 | 274 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 4.33e-21 | 135 | 270 | 165 | 302 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
| Q10983 | 9.79e-08 | 131 | 273 | 196 | 345 | Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Oryctolagus cuniculus OX=9986 GN=FUT2 PE=1 SV=1 |
| P97353 | 1.01e-07 | 131 | 273 | 194 | 343 | Galactoside 2-alpha-L-fucosyltransferase Sec1 OS=Mus musculus OX=10090 GN=Sec1 PE=2 SV=1 |
| O77487 | 1.71e-07 | 131 | 248 | 187 | 306 | Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Pongo pygmaeus OX=9600 GN=FUT2 PE=3 SV=1 |
| O77486 | 1.71e-07 | 131 | 248 | 187 | 306 | Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Gorilla gorilla gorilla OX=9595 GN=FUT2 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000081 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |