CAZyme Information: MGYG000001867_00162

Basic Information

• Species: CAG-873 sp900555715
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; CAG-873; CAG-873 sp900555715
• CAZyme ID: MGYG000001867_00162
• CAZy Family: GH76
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
691	MGYG000001867_6|CGC1	76633.86	5.0257

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001867	2424881	MAG	Denmark	Europe

• Gene Location: Start: 1680; End: 3755 Strand: -

Full Sequence      

MLYMKKILSLILAMTCIATASALTPGVAYSVGQHGRSVFISNGRPDRNADVQMWTETDVP
AQRWVLEQSDTDPRQYALRNLFSGLYLNYNGTRAGAKIRQADRSVFSSYWTLEEDGDSYV
LVPSQNAAMCLAAASTDEGAALSLQERATADAGLTRFTLRQDDVPEAFGEAVRDDFMSGF
LGQYYHKASTGHVLGGGGWWGDAEMFEVILDAFATTGDLKYKEIFDELVIDFCRRNGRDW
SNNEFNDDITWMVLACARAYKYFGTQEYLDLAKDNYTRMYNRAHQRFGTLIWKQSQENKI
ATNSCINCPATVAACMLGELTGDNSWYDKALTIYAGQRKLLYNAETGEVWDCGAWTADGE
REPGGNHWVSTYNQGTMLGAATLLYLYTKDKMYLEDAKKVYERSRDHLTNNNKIISVCQT
VNGDLCGFKGILMRYVRTYAETFHLEEPLQWMEKNAWNAWQNRNSGGVIWSAWLTKTAES
LTRKEGDDEKDVTNDAFGASTAVSVAFNAPVNRRFAKSVSEGLQPEYFDDIKFAQLTEDP
AEGRVTTPVLSGGWICFRNVDFGQDGISSLDLRLKATKARSYVQVYVDELTDDGLMGRNS
GFLTRGDWSDVVVPFKAGVTGVHDVYIRFNGDGVQAGGIKSTGSGSGVDSPVAVIGEIGS
VYNLRGIRVGSSMDGLAPGIYISGGHKILKR

Enzyme Prediction     

No EC number prediction in MGYG000001867_00162.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH76	175	482	1.1e-53	0.8659217877094972

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam03663	Glyco_hydro_76	1.18e-33	184	467	16	320	Glycosyl hydrolase family 76. Family of alpha-1,6-mannanases.
COG4833	COG4833	8.89e-12	199	442	46	280	Predicted alpha-1,6-mannanase, GH76 family [Carbohydrate transport and metabolism].
cd04084	CBM6_xylanase-like	2.68e-11	524	633	4	112	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains. This family includes carbohydrate binding module 6 (CBM6) domains that are appended mainly to glycoside hydrolase (GH) family domains, including GH3, GH11, and GH43 domains. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB6s belonging to this family are Microbispora bispora GghA, a 1,4-beta-D-glucan glucohydrolase (GH3); Clostridium thermocellum xylanase U (GH11), and Penicillium purpurogenum ABF3, a bifunctional alpha-L-arabinofuranosidase/xylobiohydrolase (GH43). GH3 comprises enzymes with activities including beta-glucosidase (hydrolyzes beta-galactosidase) and beta-xylosidase (hydrolyzes 1,4-beta-D-xylosidase). GH11 family comprises enzymes with xylanase (endo-1,4-beta-xylanase) activity which catalyze the hydrolysis of beta-1,4 bonds of xylan, the major component of hemicelluloses, to generate xylooligosaccharides and xylose. GH43 includes beta-xylosidases and beta-xylanases, using aryl-glycosides as substrates. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold.
pfam14200	RicinB_lectin_2	7.54e-07	60	144	1	88	Ricin-type beta-trefoil lectin domain-like.
smart00606	CBD_IV	1.48e-05	516	633	1	120	Cellulose Binding Domain Type IV.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QUT74831.1	3.69e-109	4	629	1	633
QIA07414.1	6.00e-77	18	633	59	661
QEC70572.1	4.37e-75	17	514	22	500
AYD48939.1	4.14e-68	8	509	6	495
QOV19890.1	8.41e-56	170	636	29	484

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5M77_A	2.06e-40	200	629	73	506	ChainA, Alpha-1,6-mannanase [Niallia circulans],5M77_B Chain B, Alpha-1,6-mannanase [Niallia circulans]
4BOK_A	8.84e-36	200	480	39	328	ChainA, Alpha-1,6-mannanase [Niallia circulans]
4BOJ_A	9.43e-36	200	480	42	331	ChainA, Alpha-1,6-mannanase [Niallia circulans],4BOJ_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4BOJ_C Chain C, Alpha-1,6-mannanase [Niallia circulans]
4D4A_A	4.73e-35	200	480	60	349	ChainA, Alpha-1,6-mannanase [Niallia circulans],4D4A_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4B_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4B_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4C_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4C_B Chain B, Alpha-1,6-mannanase [Niallia circulans],4D4D_A Chain A, Alpha-1,6-mannanase [Niallia circulans],4D4D_B Chain B, Alpha-1,6-mannanase [Niallia circulans],5N0F_A Chain A, Alpha-1,6-mannanase [Niallia circulans],5N0F_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBX_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBX_B Chain B, Alpha-1,6-mannanase [Niallia circulans],7NL5_A Chain A, Alpha-1,6-mannanase [Niallia circulans]
5AGD_A	2.21e-34	200	480	60	349	ChainA, Alpha-1,6-mannanase [Niallia circulans],5AGD_B Chain B, Alpha-1,6-mannanase [Niallia circulans],6ZBM_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_A Chain A, Alpha-1,6-mannanase [Niallia circulans],6ZBW_B Chain B, Alpha-1,6-mannanase [Niallia circulans]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000270	0.999027	0.000186	0.000185	0.000171	0.000150

TMHMM  Annotations     

start	end
7	29