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CAZyme Information: MGYG000001881_00929
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Akkermansia muciniphila_A | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia; Akkermansia muciniphila_A | |||||||||||
| CAZyme ID | MGYG000001881_00929 | |||||||||||
| CAZy Family | GH37 | |||||||||||
| CAZyme Description | Periplasmic trehalase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 24798; End: 26324 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH37 | 236 | 422 | 2.3e-24 | 0.35845213849287166 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10137 | PRK10137 | 5.83e-20 | 226 | 378 | 578 | 738 | alpha-glucosidase; Provisional |
| pfam03200 | Glyco_hydro_63 | 6.50e-19 | 166 | 424 | 195 | 487 | Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain. |
| pfam01204 | Trehalase | 9.91e-15 | 136 | 388 | 180 | 464 | Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi. |
| COG3408 | GDB1 | 1.64e-14 | 72 | 473 | 275 | 641 | Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism]. |
| COG1626 | TreA | 3.43e-11 | 203 | 378 | 325 | 498 | Neutral trehalase [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AYR29102.1 | 0.0 | 2 | 508 | 1 | 507 |
| QHV28157.1 | 0.0 | 1 | 508 | 1 | 508 |
| QHV48982.1 | 0.0 | 1 | 508 | 1 | 508 |
| QAA69012.1 | 0.0 | 1 | 508 | 1 | 508 |
| QHV25902.1 | 0.0 | 1 | 508 | 1 | 508 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3W7S_A | 8.20e-14 | 226 | 377 | 551 | 710 | Escherichiacoli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7S_B Escherichia coli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7T_A Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7T_B Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7U_A Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12],3W7U_B Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12] |
| 3W7W_A | 8.20e-14 | 226 | 377 | 551 | 710 | Crystalstructure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],3W7W_B Crystal structure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],5GW7_A Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5GW7_B Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12] |
| 3W7X_A | 8.20e-14 | 226 | 377 | 551 | 710 | Crystalstructure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],3W7X_B Crystal structure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],5CA3_A Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5CA3_B Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12] |
| 7PQQ_B | 8.99e-14 | 226 | 377 | 100 | 259 | ChainB, Anti-RON nanobody,Megabody 91,Glucosidase YgjK [Lama glama] |
| 6XUX_A | 9.00e-14 | 226 | 377 | 100 | 259 | ChainA, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody [Escherichia coli K-12] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P94250 | 1.36e-32 | 38 | 451 | 3 | 407 | Uncharacterized protein BB_0381 OS=Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326 GN=BB_0381 PE=4 SV=2 |
| P42592 | 4.57e-13 | 226 | 377 | 574 | 733 | Glucosidase YgjK OS=Escherichia coli (strain K12) OX=83333 GN=ygjK PE=1 SV=1 |
| P49381 | 1.19e-10 | 255 | 403 | 534 | 697 | Cytosolic neutral trehalase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=NTH1 PE=1 SV=1 |
| A0A384JRP0 | 6.19e-10 | 238 | 421 | 501 | 692 | Cytosolic neutral trehalase OS=Botryotinia fuckeliana (strain B05.10) OX=332648 GN=TRE1 PE=3 SV=1 |
| O42777 | 2.82e-07 | 249 | 403 | 522 | 691 | Cytosolic neutral trehalase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=treB PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000302 | 0.999011 | 0.000202 | 0.000177 | 0.000144 | 0.000139 |