CAZyme Information: MGYG000001896_01337

Basic Information

• Species: UMGS1840 sp900555525
• Lineage: Bacteria; Firmicutes_A; Clostridia; UMGS1840; UMGS1840; UMGS1840; UMGS1840 sp900555525
• CAZyme ID: MGYG000001896_01337
• CAZy Family: GH127
• CAZyme Description: Non-reducing end beta-L-arabinofuranosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
523	MGYG000001896_95|CGC1	60382.94	5.4407

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001896	2208881	MAG	Denmark	Europe

• Gene Location: Start: 2639; End: 4210 Strand: -

Full Sequence      

MYENRDEKLEKIIDDVVDLIAKNRDENGYFNSYYLTVAPEKKFTIRDNHELYCAGHLMEA
AIAYYESTGKDKFLKVMCKYADYIDKVFRIEKSAAYFTPGHPEIELALIRLYDATSEERY
LKLAEYFIDEHGKHIELLPKNCTLSYNQDEIPLTDITEAKGHCVRALYLYCGMIDVAQKR
NDEKLYHACERVFEKIINKKMYITGGVGSSRYGEAFTIDYDLPNRKAYAESCAAIGLCMF
AHRMQKTYISSKYADTIERVIYNGFLSSMSMDGKKFFYENPLAVDPVFNHTVKDEIYPIT
ERVEVFSCSCCPPNIVRFIPSIGDYLYSCNDEAVFVHQFMESEAEFDGISIRQKTNYPID
GNIHINCDTKGKKLAIRIPYWVKKFKINKEYTLKDGYAYIEDAKDEISVTFDLSVNIIRS
NPKVHENAGRVAVMRGPVVYCAEGVDNGENIFDIMIDTKSKFSEEKSEFMLPSLVCTAYE
PLNTDELYPTDSDNLKKRSLKLIPYYAFANRGTSEMEVWILKK

Enzyme Prediction     

No EC number prediction in MGYG000001896_01337.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH127	3	441	7.1e-161	0.8664122137404581

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3533	COG3533	7.90e-149	1	520	78	585	Uncharacterized conserved protein, DUF1680 family [Function unknown].
pfam07944	Glyco_hydro_127	5.10e-131	1	441	70	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG1331	YyaL	0.006	57	130	415	499	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AUS96918.1	7.01e-164	1	523	83	628
QNF29330.1	3.17e-155	7	523	91	644
ADH61394.1	3.94e-154	6	523	96	648
QHQ63226.1	1.59e-153	1	521	80	623
AVK51332.1	9.47e-153	4	522	92	648

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4QJY_A	5.37e-147	5	523	94	648	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
4QK0_A	4.34e-140	5	523	94	648	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
6EX6_A	1.47e-104	6	520	88	623	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
3WRE_A	1.05e-103	6	519	94	655	Thecrystal structure of native HypBA1 from Bifidobacterium longum JCM 1217 [Bifidobacterium longum subsp. longum JCM 1217],3WRG_A The complex structure of HypBA1 with L-arabinose [Bifidobacterium longum subsp. longum JCM 1217]
3WKW_A	1.39e-103	6	519	94	655	Crystalstructure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum ligand free form [Bifidobacterium longum subsp. longum JCM 1217],3WKX_A Crystal structure of GH127 beta-L-arabinofuranosidase HypBA1 from Bifidobacterium longum arabinose complex form [Bifidobacterium longum subsp. longum JCM 1217],7BZL_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7DIF_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXV_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217],7EXW_A Chain A, Non-reducing end beta-L-arabinofuranosidase [Bifidobacterium longum subsp. longum JCM 1217]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
E8MGH8	5.74e-103	6	519	94	655	Non-reducing end beta-L-arabinofuranosidase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=hypBA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000037	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001896_01337.