CAZyme Information: MGYG000001901_00263

Basic Information

• Species: CAG-557 sp000435275
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; CAG-557; CAG-557 sp000435275
• CAZyme ID: MGYG000001901_00263
• CAZy Family: GT2
• CAZyme Description: N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
259		30388.08	8.9984

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001901	1217394	MAG	Denmark	Europe

• Gene Location: Start: 78138; End: 78917 Strand: +

Full Sequence      

MKKISICIVTYNNENNILNVLECIYKHSKNFELETFVVDSNSSDETVALVKKNFPQVNLI
VLPKNRGFGYGHNQVLNTINSDFHVILNPDITFDTNIFDELSSYLKNNSDVAMVVPQILN
SDGSIQDLPRCAPKFKYLISGRLERFCRLFKLWRDEYTCKVKNFDKPTEIDFCSGCFIMI
RTDVFKKLNGFDERFFMYFEDADLTRRAKNYGKTVLNPSFCATHTWERTSSKKFKYLCIH
ISSMLKYLKKWYRKGEIKQ

Enzyme Prediction     

No EC number prediction in MGYG000001901_00263.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	5	187	1.2e-17	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04186	GT_2_like_c	5.27e-44	6	224	1	164	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	7.77e-42	1	257	2	253	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
cd02526	GT2_RfbF_like	9.01e-16	8	247	3	226	RfbF is a putative dTDP-rhamnosyl transferase. Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.
COG1215	BcsA	2.26e-14	1	223	53	263	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd00761	Glyco_tranf_GTA_type	4.07e-14	6	213	1	152	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAB1238943.1	9.98e-81	1	251	1	251
QHT48025.1	1.60e-59	4	251	7	254
QUC68328.1	2.66e-57	4	251	5	252
QUA54184.1	2.66e-57	4	251	5	252
QTE70905.1	1.50e-56	4	251	5	252

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P9WMY2	9.41e-11	33	212	33	222	N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=wbbL PE=3 SV=2
P9WMY3	9.41e-11	33	212	33	222	N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=wbbL PE=1 SV=2
P36667	2.01e-09	4	248	2	244	Rhamnosyltransferase WbbL OS=Escherichia coli (strain K12) OX=83333 GN=wbbL PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000040	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001901_00263.