CAZyme Information: MGYG000001925_02303

Basic Information

• Species: Phocaeicola sp900544675
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900544675
• CAZyme ID: MGYG000001925_02303
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
988		110772.44	7.0615

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001925	3441241	MAG	Denmark	Europe

• Gene Location: Start: 13107; End: 16073 Strand: +

Full Sequence      

MKRAFVFWISLWVAIWGYSQTQPAIISQIKDTTACRRWVESRLEEMTLKQKIGQLFIHTI
DPLTTQRNKTQLRKAIEEYGLGGLLFAKGETGKQVQLTNLAQQWSRIPLLITFDGEWGLA
MRLKDTPEFPKNRVLGCIQNDSLIYRYGREVARQLRAIGVQVNFAPVADVDNNPANPVIN
TRSFGSSPENVARKVIAYARGLEDGGVLAVCKHFPGHGDTDVDSHLALPVLNFDRVRMDS
IELYPFKKAVEAGVSGMMVGHLQIPDLCEKPASISSNIITSLLRDEFHFSGLVFTDALEM
KGIRQAKDVSVQALLAGNDLLLVPRNLKKEMASVLDAVKKGMLTEALITEKCRKVLTYKY
ALGLDKRPLIDEEGLEACIHVPETDSLLAALDKAAVTVLKDSLEMLPLDLALSGNVLLSI
SPSLTEAYPFYQELKKSLEMGWVYAQADSLEVIRERLRSAQQVIVALHQQDYEPYLSLIH
ELAVDKPVAVVSFVPQRALTDMVPVLRQASSVVLAHTDTKTVQRYVADVLTGKVLADGRL
SVSLSDTWQAGTGVTLDPEHPYLYVPEDFGMDSRVLARIDTIAEEGIRAQAYPGCHVLIL
KDGYPVYNKCFGRFTYDDSPEVKENSLYDLASLSKVTGTLLAVMKLYDEGKFGLTDRVSQ
YLPMLRGTRKERITIQDLLYHESGLPAYWSFYQDAIDLKSCKGGLFRKKRDKHHLLQVDE
NLYACTDFAYKKEWVSAVPSAQYALRLSDSLYLNVGFPEEMNRRLVDVPLKGHSYRYSCL
NFMLLKELVEELAQVPMDVYLDSVFYKPMGLTHTAYNPLRRFDKSQIVPTAAHDFLRGGE
LQGYVNDEIAAFMGGVSGNAGLFSTAHDVAVIFRMLLDKGVCGDRRYLSRATCELFIGMQ
SKESRRGLGFDKPDKENPDKSPCAAEAPRSVFGHTGFTGTCTWADPDNGLVFVFLSNRTY
PQAFDHKNLTKLDIRTRMQQAMYQSLKH

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	101	323	6e-60	0.9861111111111112

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	1.64e-79	46	423	1	363	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	5.66e-75	47	357	1	315	Glycosyl hydrolase family 3 N terminal domain.
PRK03642	PRK03642	1.92e-60	566	958	30	395	putative periplasmic esterase; Provisional
pfam00144	Beta-lactamase	2.18e-41	579	970	1	320	Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
COG1680	AmpC	1.73e-36	571	985	34	390	CubicO group peptidase, beta-lactamase class C family [Defense mechanisms].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADY37542.1	0.0	1	987	1	986
QRO23705.1	0.0	8	986	7	986
QUT56867.1	0.0	1	986	1	990
QEW35592.1	0.0	1	986	1	990
QQY39794.1	0.0	1	986	1	990

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6K5J_A	2.39e-62	46	547	11	534	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
3SQL_A	4.45e-57	43	389	12	373	CrystalStructure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQL_B Crystal Structure of Glycoside Hydrolase from Synechococcus [Synechococcus sp. PCC 7002],3SQM_A Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_B Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_C Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002],3SQM_D Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine [Synechococcus sp. PCC 7002]
3BMX_A	1.32e-56	31	439	25	469	Beta-N-hexosaminidase(YbbD) from Bacillus subtilis [Bacillus subtilis],3BMX_B Beta-N-hexosaminidase (YbbD) from Bacillus subtilis [Bacillus subtilis],3NVD_A Structure of YBBD in complex with pugnac [Bacillus subtilis],3NVD_B Structure of YBBD in complex with pugnac [Bacillus subtilis]
4GYJ_A	6.69e-56	31	439	29	473	Crystalstructure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYJ_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1) [Bacillus subtilis subsp. subtilis str. 168],4GYK_A Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168],4GYK_B Crystal structure of mutant (D318N) bacillus subtilis family 3 glycoside hydrolase (nagz) in complex with glcnac-murnac (space group P1211) [Bacillus subtilis subsp. subtilis str. 168]
3LK6_A	9.72e-56	33	439	1	443	ChainA, Lipoprotein ybbD [Bacillus subtilis],3LK6_B Chain B, Lipoprotein ybbD [Bacillus subtilis],3LK6_C Chain C, Lipoprotein ybbD [Bacillus subtilis],3LK6_D Chain D, Lipoprotein ybbD [Bacillus subtilis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P40406	7.24e-56	31	439	25	469	Beta-hexosaminidase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagZ PE=1 SV=1
P48823	1.31e-46	71	466	54	485	Beta-hexosaminidase A OS=Pseudoalteromonas piscicida OX=43662 GN=cht60 PE=1 SV=1
B5R4I5	5.44e-44	559	960	21	397	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella enteritidis PT4 (strain P125109) OX=550537 GN=yfeW PE=3 SV=1
B5RCU8	7.37e-44	559	960	21	397	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=yfeW PE=3 SV=1
Q8Z4S7	7.37e-44	559	960	21	397	Putative D-alanyl-D-alanine carboxypeptidase OS=Salmonella typhi OX=90370 GN=yfeW PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000313	0.999091	0.000165	0.000141	0.000134	0.000136

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001925_02303.