CAZyme Information: MGYG000001948_00146

Basic Information

• Species: Muribaculum sp002492595
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Muribaculaceae; Muribaculum; Muribaculum sp002492595
• CAZyme ID: MGYG000001948_00146
• CAZy Family: GH146
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
790	MGYG000001948_1|CGC6	89100.57	6.1909

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001948	2811075	MAG	Denmark	Europe

• Gene Location: Start: 173226; End: 175598 Strand: -

Full Sequence      

MNYRHFLAAGAMLLAAMSPLSAQQRLYPNEFSLSDVQLLDGPFKHACDLNVDVLLQYDVD
RLLAPFLKEAGLQPKGELFPNWEGLDGHVGGHYLSALAIHYAATGNEKLKSRMDYMISEL
KRCQDANGNGYIGGVPNGAKLWKEIHDGNVGIVWKYWVPWYNVHKTYAGLRDAWVYTGDK
QARDMFLKLCDWGIDVIAPLDDKQMEAMLDNEFGGMDEVYADAYAMTGDKRYLDAAKRFA
HHWLLDSMAAGVDNLDNKHANTQVPKVVGYQRIAELDGDKTFDSAARFFWNTVVHDRSLS
IGGNSRREHFASAADCKSYADDREGPESCNTNNMLKLTEGLFRMSPTAEYADFYERALFN
HILSTQHPEHGGYVYFTSARPGHYRVYSQPNSAMWCCVGTGMENHGKYGQFIYTHSGDSL
QVNLFIASRLNWRDKGVTLTQSTSFPDSESSRLVVNTRGKKKFKLQLRHPGWCEGMTVKV
NGKEIAASLAQSYVTIDRTWRDGDVVELSLPMAVTVEEIPNVPDYISIVRGPIVMGARYS
TENLDGLVGDDGRWAHIASGPLVSVFDTPLLIGTRDEILKKLNNMKPVEGKSMTYTVPGL
FDAKYASLELEPFARIHDCRYMMYWLSMTPEQYASYLREEQLKEEMRLALDRRTVDAVNT
GEQQPEVDHGMKFDRSNKGNFQGEPWRDASNGGFFSYMLSTDNLDSLALMVRYWGNENGK
RTFDILVDDTLLASENVSGKWKRDEFVNVEYPIPADLLAGKSHVTVTFRSHPGHSAGGIY
HVRLIKSEEK

Enzyme Prediction     

EC	3.2.1.185

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH146	35	535	6.3e-204	0.9960238568588469

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	0.0	35	534	1	501	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
COG3533	COG3533	5.48e-126	36	641	12	589	Uncharacterized conserved protein, DUF1680 family [Function unknown].
pfam16375	DUF4986	2.43e-36	541	625	2	84	Domain of unknown function. This family around 150 residues locates in the C-terminal of some uncharacterized proteins in various Bacteroides and Bacillus species. The function of this family remains unknown.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QCD36520.1	0.0	1	790	1	790
ADY37333.1	0.0	13	786	11	796
QCD43163.1	0.0	12	788	7	787
SCV06553.1	0.0	15	788	16	799
QRQ58640.1	0.0	15	788	16	799

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6YQH_AAA	3.36e-225	13	786	10	802	ChainAAA, Acetyl-CoA carboxylase, biotin carboxylase [Bacteroides thetaiotaomicron VPI-5482]
5OPJ_A	1.42e-218	13	786	10	802	Beta-L-arabinofuranosidase[Bacteroides thetaiotaomicron]
4QJY_A	1.44e-21	273	545	279	565	Crystalstructure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QJY_B Crystal structure of native Ara127N, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]
6EX6_A	4.39e-21	224	539	203	548	TheGH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482],6EX6_B The GH127, Beta-arabinofuranosidase, BT3674 [Bacteroides thetaiotaomicron VPI-5482]
4QK0_A	1.02e-20	273	545	279	565	Crystalstructure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_B Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_C Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus],4QK0_D Crystal structure of Ara127N-Se, a GH127 beta-L-arabinofuranosidase from Geobacillus Stearothermophilus T6 [Geobacillus stearothermophilus]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.001085	0.996374	0.001839	0.000293	0.000209	0.000169

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001948_00146.