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CAZyme Information: MGYG000001963_01077

You are here: Home > Sequence: MGYG000001963_01077

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola sp000434735
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp000434735
CAZyme ID MGYG000001963_01077
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
665 MGYG000001963_18|CGC1 77139.86 9.1877
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001963 3288738 MAG Denmark Europe
Gene Location Start: 30236;  End: 32233  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL12 403 533 1.3e-64 0.9923664122137404

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 0.0 29 382 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 1.12e-37 393 617 2 234
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIU95106.1 0.0 3 664 5 666
QUT22704.1 0.0 3 664 5 666
QRM98073.1 0.0 3 664 5 666
ANU56961.1 0.0 3 664 5 666
QQR18181.1 0.0 3 664 5 666

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5JMD_A 0.0 21 664 11 655
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 0.0 21 664 11 655
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMI_A 4.54e-189 29 665 10 637
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]
4MMH_A 9.10e-189 29 658 10 630
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4FNV_A 9.21e-121 27 664 48 702
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C7EXL6 0.0 4 664 6 666
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 2.97e-188 15 658 20 654
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1
Q89YR9 5.04e-120 27 664 48 702
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001822 0.846197 0.151187 0.000298 0.000243 0.000239

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001963_01077.