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CAZyme Information: MGYG000001977_00496

You are here: Home > Sequence: MGYG000001977_00496

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides;
CAZyme ID MGYG000001977_00496
CAZy Family GH97
CAZyme Description Glucan 1,4-alpha-glucosidase SusB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
738 MGYG000001977_10|CGC3 84330.79 5.7659
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001977 4322077 MAG Denmark Europe
Gene Location Start: 39168;  End: 41384  Strand: +

Full Sequence      Download help

MKLKKNLSLI  AFLCISFIAN  AQQKLSSPDG  NLEMTFTLDG  QGTPTYELTY  KQKEVIKPSR60
LGLELKKEDA  NAKTDFEWTD  KKDIDKLDIK  TNLYNGFELK  DVQTSTNDET  WQPVWGEEKE120
IRNHYNELAV  TLNQPANDRF  IIIRFRLFND  GLGFRYEFPQ  QKNLNYFVIK  EEHSQFAMAG180
DHTAYWIPGD  YDTQEYDYTV  SRLSEIRGLF  SKAYTENSSQ  TAFSPTGVQT  ALMMKTDDGL240
YINLHEAALI  DYACMHLNLD  DKNMIFESWL  TPDAQGDKGY  MQTPCTSPWR  TVIVSDDARN300
ILASRITLNL  NEPCKIADTS  WIKPVKYIGV  WWDMITGKGS  WAYTDDLSSV  KLGETDYNKT360
KPNGKHSANT  ANVKRYIDFA  AEHGFDQVLV  EGWNEGWEDW  FGKSKDYVFD  FVTPYPDFNV420
KELQSYAASK  GVKLMMHHET  SASVRNYERH  MDQAYQFMAD  NGYNSVKSGY  VGNIIPRGEH480
HYGQWMDNHY  LYAVKKAADY  KIMVNAHEAV  RPTGICRTYP  NLIGNESARG  TEYESFGGNN540
VNHTTILPFT  RLIGGPMDYT  PGIFETRCNK  MNPTNNSQVR  STLARQLALY  VTMYSPLQMA600
ADIPENYERF  MDAFQFIKDV  AIDWDETKYL  EAEPGDYITI  ARKAKGTNDW  YIGCTADENG660
HSSKLIFDFL  DPDKKYIATV  YADAKDADWK  DNPQAYTIRK  GIVTNKSKLN  LHAASGGGYA720
ISIKEVKDKS  ELKGIKRL738

Enzyme Prediction      help

EC 3.2.1.3 3.2.1.20

CAZyme Signature Domains help

Created with Snap367311014718422125829533236940544247951655359062766470112723GH97
Family Start End Evalue family coverage
GH97 12 723 2.3e-258 0.9920760697305864

CDD Domains      download full data without filtering help

Created with Snap3673110147184221258295332369405442479516553590627664701318621Glyco_hydro_9727313GH97_N624724GH97_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam10566 Glyco_hydro_97 5.23e-148 318 621 1 278
Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.
pfam14508 GH97_N 7.34e-103 27 313 1 235
Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole.
pfam14509 GH97_C 1.86e-45 624 724 1 97
Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site.

CAZyme Hits      help

Created with Snap36731101471842212582953323694054424795165535906276647011738ALA72849.1|GH971738QJR61692.1|GH971738AII67018.1|GH971738QJR53512.1|GH971738AND18771.1|GH97
Hit ID E-Value Query Start Query End Hit Start Hit End
ALA72849.1 0.0 1 738 1 738
QJR61692.1 0.0 1 738 1 738
AII67018.1 0.0 1 738 1 738
QJR53512.1 0.0 1 738 1 738
AND18771.1 0.0 1 738 1 738

PDB Hits      download full data without filtering help

Created with Snap3673110147184221258295332369405442479516553590627664701197382D73_A247382JKA_A227383WFA_A257245HQ4_A257245HQC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2D73_A 0.0 19 738 19 738
CrystalStructure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2D73_B Crystal Structure Analysis of SusB [Bacteroides thetaiotaomicron VPI-5482],2ZQ0_A Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron],2ZQ0_B Crystal structure of SusB complexed with acarbose [Bacteroides thetaiotaomicron]
2JKA_A 0.0 24 738 13 727
Nativestructure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKA_B Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JKE_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKE_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin [Bacteroides thetaiotaomicron VPI-5482],2JKP_A Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482],2JKP_B Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine [Bacteroides thetaiotaomicron VPI-5482]
3WFA_A 0.0 22 738 2 718
Catalyticrole of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron],3WFA_B Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase [Bacteroides thetaiotaomicron]
5HQ4_A 1.18e-170 25 724 3 659
AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]
5HQC_A 1.18e-170 25 724 3 659
AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8]

Swiss-Prot Hits      download full data without filtering help

Created with Snap36731101471842212582953323694054424795165535906276647011738sp|G8JZS4|SUSB_BACTN9724sp|Q8A6L0|AGAL_BACTN26720sp|D7CFN7|AGAL_STRBB
Hit ID E-Value Query Start Query End Hit Start Hit End Description
G8JZS4 0.0 1 738 1 738
Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1
Q8A6L0 2.28e-67 9 724 8 662
Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1
D7CFN7 6.75e-30 26 720 44 617
Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000414 0.998603 0.000378 0.000190 0.000200 0.000180

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001977_00496.