CAZyme Information: MGYG000002080_01955

Basic Information

• Species: Prevotella sp900544825
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900544825
• CAZyme ID: MGYG000002080_01955
• CAZy Family: GH84
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
845	MGYG000002080_42|CGC1	95459.59	7.5679

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002080	3221264	MAG	Netherlands	Europe

• Gene Location: Start: 10154; End: 12691 Strand: -

Full Sequence      

MTRKVIFAAMLMAAFAQGTQAQDLSGQRSEKQDVHMIPGKKLDHHGLIVSPTPHLLNVDA
ANRLDLQKGVKVIDKKGKFADDVKFLTANAKGIRLTIDFGEKLAAKAGVKPVSGAYSLKA
DAKGIQIVGYDERGAFYGLQTLRQIVNSEMAKGQMPYTTCNDYPDLPNRGVVEGFYGEPW
SHQVRLSLIDYYGKNKMNTYLYGPKDDPYHSCPNWRLPYPEKEAKNISELVQACRRNRVD
FVWAIHPGQDIKWNEEDYQNLVHKLDLMYDLGVRSFAIFFDDISGEGANPVKQSELLNRL
TKEFVKAKGDVTPLVMCPTDYTRLWANPKPTGSLAIFGNTLDPSINVFWTGDVVCSDLTR
ETLDWVNSRIKRPAYYWWNFPVTDYARHIIMQGPTYGLQTDLTNKDLCGFVSNPMEHGEA
SKLALYGVADYTWNIANYNPLDNWERGLVDLTPEAHEAYRTFAMHSCDTETGYRRIESWE
TKSFRIDNFTDAEFNALQSEFVRVKNAPAQMEANCKNALLMKELRPWLTEFGKLGDRGLK
TMQLIKEYKAGNDQAFWDGYVNNRMSKEDVAAYEKHKSGTMVLQPFYEQSMDDMASGFFK
KLTGKVPAFYKGIGTYATLRTTQSKAMFDNDSTTYYTSGNGQNTGDWIGADLGCVRSVSE
VRILQGRNSVDDVDYFDNTVLEYSLDKKEWKALTGELKKQYIINWKTDSPVEARYIRIKK
LKSDKRNWAAVRTFEVNPTTPDCLSFPVEAGNLQAAMYGFDENPCTSFTNEGTLTMGVEK
AVKGYTLLLKLAPGKSLVCRQLNAKGKVLATINIDQSFCKIELVKKAAKVQLDGSAEIFE
IIPEK

Enzyme Prediction     

No EC number prediction in MGYG000002080_01955.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH84	169	463	3.2e-106	0.9932203389830508

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07555	NAGidase	7.36e-167	169	462	1	293	beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838	Glyco_hydro_20b	1.33e-11	51	162	6	123	Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
pfam00754	F5_F8_type_C	2.25e-09	626	732	16	124	F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
cd00057	FA58C	1.19e-06	628	736	29	141	Substituted updates: Jan 31, 2002
COG3525	Chb	0.002	35	223	115	316	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ALB75783.1	0.0	2	842	11	850
BCI62100.1	0.0	23	844	31	854
AHF11939.1	0.0	3	845	5	855
ADV43394.1	0.0	3	842	4	847
BBL05673.1	0.0	2	842	4	844

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2J4G_A	1.57e-153	116	608	80	585	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482],2J4G_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482]
5MI4_A	1.59e-153	116	608	92	597	BtGH84mutant with covalent modification by MA3 [Bacteroides thetaiotaomicron VPI-5482],5MI5_A BtGH84 mutant with covalent modification by MA3 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],5MI6_A BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G [Bacteroides thetaiotaomicron VPI-5482],5MI7_A BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482]
2JIW_A	1.61e-153	116	608	81	586	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482],2JIW_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482]
2CHO_A	1.61e-153	116	608	81	586	Bacteroidesthetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482],2CHO_B Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482]
2J47_A	1.61e-153	116	608	81	586	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor [Bacteroides thetaiotaomicron VPI-5482],2W4X_A BtGH84 in complex with STZ [Bacteroides thetaiotaomicron VPI-5482],2W66_A BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W66_B BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W67_A BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2W67_B BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2WCA_A BtGH84 in complex with n-butyl pugnac [Bacteroides thetaiotaomicron VPI-5482],2XJ7_A BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XJ7_B BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XM1_A BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM1_B BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM2_A BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],2XM2_B BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],4UR9_A Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],4UR9_B Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],5FKY_A Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FKY_B Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FL0_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL0_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q89ZI2	1.65e-152	116	608	102	607	O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q0TR53	3.35e-91	116	520	133	548	O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08	2.33e-90	116	520	133	548	O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
P26831	1.34e-51	125	737	143	795	Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
O60502	5.32e-37	170	439	63	337	Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000264	0.998970	0.000231	0.000186	0.000165	0.000141

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002080_01955.