CAZyme Information: MGYG000002089_00377

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UMGS1826
• CAZyme ID: MGYG000002089_00377
• CAZy Family: GH109
• CAZyme Description: Alpha-N-acetylgalactosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
414		46886.22	5.2039

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002089	1650359	MAG	Mongolia	Asia

• Gene Location: Start: 117; End: 1361 Strand: +

Full Sequence      

MKEKLNIGFIGLGGRGYGLLKGIVIPREEINVLAVCDLYEDRRENGAKLVKEKKGNEPLC
TADYREILAIDEIDAIIVATSWADHLHIVIDAMKAGKYVATEVGGAYSLDECWELVRTHE
ETGVPCMMLENCCYDRNELMVLNMVKQGIFGDVVHCQGGYRHDLRSEIAFGRENRHYRLV
NYMNRNCENYPTHELGPIAKVLNINRGNRMLTLNSIASKSAGLHQFLMDQKGPDYDLTNA
EWTQGDVITTVIKCAHGETIVLTLDTTLPRSYSRGFHIQGTKAMFDEDTRSLFIDGEHNQ
FDFDWSTQWNNVEQYREKYEHPIWRDYLKEGITGGHGGIDWLVFNAFFDAVKRGTQTPID
VYDMAAWMSITPLSAQSIAQGGAPVAIPDFTNGRWINREPAVEGIYCLEKVCEK

Enzyme Prediction     

No EC number prediction in MGYG000002089_00377.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH109	3	397	5.1e-148	0.9874686716791979

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0673	MviM	2.18e-16	32	389	32	342	Predicted dehydrogenase [General function prediction only].
pfam01408	GFO_IDH_MocA	9.77e-09	41	128	33	118	Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilize NADP or NAD. This family is called the GFO/IDH/MOCA family in swiss-prot.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QTH41319.1	5.65e-197	1	401	4	403
QJD87109.1	1.25e-196	1	396	1	395
QTH43530.1	1.66e-192	1	398	1	398
ALS29040.1	2.72e-192	1	400	1	400
QNK55026.1	9.21e-192	1	399	1	398

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2IXA_A	6.48e-109	3	397	19	433	A-zyme,N-acetylgalactosaminidase [Elizabethkingia meningoseptica],2IXB_A Crystal structure of N-ACETYLGALACTOSAMINIDASE in complex with GalNAC [Elizabethkingia meningoseptica]
6T2B_A	8.20e-79	4	400	42	443	Glycosidehydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. [Akkermansia muciniphila],6T2B_B Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. [Akkermansia muciniphila],6T2B_C Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. [Akkermansia muciniphila],6T2B_D Glycoside hydrolase family 109 from Akkermansia muciniphila in complex with GalNAc and NAD+. [Akkermansia muciniphila]
3E18_A	3.56e-07	3	157	4	150	CRYSTALSTRUCTURE OF NAD-BINDING PROTEIN FROM Listeria innocua [Listeria innocua],3E18_B CRYSTAL STRUCTURE OF NAD-BINDING PROTEIN FROM Listeria innocua [Listeria innocua]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A4Q8F7	3.55e-108	3	397	19	433	Alpha-N-acetylgalactosaminidase OS=Elizabethkingia meningoseptica OX=238 GN=nagA PE=1 SV=1
A4Q8G1	8.50e-98	5	401	53	465	Alpha-N-acetylgalactosaminidase OS=Tannerella forsythia OX=28112 GN=nagA PE=3 SV=1
A6LB54	6.36e-97	4	400	49	462	Glycosyl hydrolase family 109 protein OS=Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152) OX=435591 GN=BDI_1155 PE=3 SV=1
B2FLK4	1.78e-96	3	406	32	454	Glycosyl hydrolase family 109 protein OS=Stenotrophomonas maltophilia (strain K279a) OX=522373 GN=Smlt4431 PE=3 SV=1
Q01S58	1.55e-90	5	400	43	437	Glycosyl hydrolase family 109 protein OS=Solibacter usitatus (strain Ellin6076) OX=234267 GN=Acid_6590 PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000051	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002089_00377.