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CAZyme Information: MGYG000002135_01425

You are here: Home > Sequence: MGYG000002135_01425

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Anaeromassilibacillus sp002159845
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Anaeromassilibacillus; Anaeromassilibacillus sp002159845
CAZyme ID MGYG000002135_01425
CAZy Family CBM32
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
2227 243986.66 4.041
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002135 2740278 MAG United States North America
Gene Location Start: 60422;  End: 67105  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002135_01425.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH2 332 1017 4.4e-61 0.699468085106383
CBM32 49 173 2.5e-24 0.967741935483871
CBM6 1249 1376 4e-24 0.8840579710144928

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd04084 CBM6_xylanase-like 1.26e-26 1250 1375 2 123
Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains. This family includes carbohydrate binding module 6 (CBM6) domains that are appended mainly to glycoside hydrolase (GH) family domains, including GH3, GH11, and GH43 domains. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB6s belonging to this family are Microbispora bispora GghA, a 1,4-beta-D-glucan glucohydrolase (GH3); Clostridium thermocellum xylanase U (GH11), and Penicillium purpurogenum ABF3, a bifunctional alpha-L-arabinofuranosidase/xylobiohydrolase (GH43). GH3 comprises enzymes with activities including beta-glucosidase (hydrolyzes beta-galactosidase) and beta-xylosidase (hydrolyzes 1,4-beta-D-xylosidase). GH11 family comprises enzymes with xylanase (endo-1,4-beta-xylanase) activity which catalyze the hydrolysis of beta-1,4 bonds of xylan, the major component of hemicelluloses, to generate xylooligosaccharides and xylose. GH43 includes beta-xylosidases and beta-xylanases, using aryl-glycosides as substrates. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold.
smart00606 CBD_IV 6.72e-25 1244 1375 1 129
Cellulose Binding Domain Type IV.
pfam00754 F5_F8_type_C 1.57e-23 63 173 14 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
pfam03422 CBM_6 7.16e-23 1252 1377 1 125
Carbohydrate binding module (family 6).
COG3250 LacZ 2.98e-22 392 757 61 428
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QJE27274.1 1.47e-196 337 1239 24 921
BBK91423.1 1.10e-195 337 1239 15 912
BBE17052.1 2.56e-195 359 1256 56 958
QIX67210.1 1.02e-194 337 1239 24 921
QUR50384.1 1.97e-194 337 1239 24 921

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2V72_A 4.27e-21 42 176 11 142
Thestructure of the family 32 CBM from C. perfringens NanJ in complex with galactose [Clostridium perfringens]
4A41_A 6.16e-20 42 177 25 161
CpGH89CBM32-5,from Clostridium perfringens, in complex with galactose [Clostridium perfringens],4A44_A CpGH89CBM32-5, from Clostridium perfringens, in complex with the Tn Antigen [Clostridium perfringens],4A45_A CpGH89CBM32-5, from Clostridium perfringens, in complex with GalNAc- beta-1,3-galactose [Clostridium perfringens],4AAX_A CpGH89CBM32-5, from Clostridium perfringens, in complex with N- acetylgalactosamine [Clostridium perfringens]
2J7M_A 2.83e-19 50 161 14 124
Characterizationof a Family 32 CBM [Clostridium perfringens]
2J1A_A 2.91e-19 50 161 15 125
Structureof CBM32 from Clostridium perfringens beta-N- acetylhexosaminidase GH84C in complex with galactose [Clostridium perfringens ATCC 13124],2J1E_A High Resolution Crystal Structure of CBM32 from a N-acetyl-beta- hexosaminidase in complex with lacNAc [Clostridium perfringens ATCC 13124]
2V5D_A 1.23e-16 50 161 602 712
Structureof a Family 84 Glycoside Hydrolase and a Family 32 Carbohydrate-Binding Module in Tandem from Clostridium perfringens. [Clostridium perfringens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8XL08 5.03e-16 50 205 632 793
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q0TR53 8.64e-16 50 161 632 742
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
I1S2N3 3.19e-15 66 184 71 195
Galactose oxidase OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=GAOA PE=3 SV=1
P0CS93 4.19e-15 66 184 71 195
Galactose oxidase OS=Gibberella zeae OX=5518 GN=GAOA PE=1 SV=1
P33558 1.06e-14 1246 1513 248 504
Endo-1,4-beta-xylanase A OS=Thermoclostridium stercorarium OX=1510 GN=xynA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000920 0.997332 0.000226 0.001048 0.000238 0.000202

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002135_01425.