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CAZyme Information: MGYG000002141_00074

You are here: Home > Sequence: MGYG000002141_00074

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-95 sp900554925
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; CAG-95; CAG-95 sp900554925
CAZyme ID MGYG000002141_00074
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
319 MGYG000002141_1|CGC5 37258.42 5.0836
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002141 2542393 MAG United States North America
Gene Location Start: 80853;  End: 81812  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.69

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 1 298 1.6e-61 0.9492753623188406

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.15e-54 1 295 1 260
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 1.42e-15 8 290 8 278
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADL35260.1 3.68e-76 1 307 1 288
AOZ97425.1 1.94e-70 1 307 1 288
SNX52916.1 1.13e-56 1 295 1 273
AMQ00833.1 1.33e-47 1 304 1 277
AFK06870.1 2.03e-47 1 291 1 269

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 8.67e-25 6 290 5 285
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000074 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002141_00074.