CAZyme Information: MGYG000002242_00127

Basic Information

• Species: Treponema_D succinifaciens
• Lineage: Bacteria; Spirochaetota; Spirochaetia; Treponematales; Treponemataceae; Treponema_D; Treponema_D succinifaciens
• CAZyme ID: MGYG000002242_00127
• CAZy Family: GH18
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
318	MGYG000002242_1|CGC4	36296.67	6.0634

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002242	2466093	MAG	Peru	South America

• Gene Location: Start: 137263; End: 138219 Strand: -

Full Sequence      

MKKVITFIALTVLSACAFSQNKIKFNETWSYVLTGYENEFSADLPITDLCYFSAEINEYG
EIPSIPNRETVPPEFNGRVHIVAICESRSLSHFVIDPKYKVSKKIIKTLAEATKDFDGLQ
IDFELVPKRDAENFKVFLKKLKKAIGKDKMLSVCVPARTKTVQDDVYDYKELSSCADRIF
IMAYDQHWATSAPGPVSGMDWCKKIADHALNTIPVEKIIMGLPFYGRSWTEPNFSKAWYN
SGINRILGENSALEEVQRTEGIPHFEFKTEITVKGWFDDKESLAARCLMLSEKNIPNAGF
WRIGQEDKEFWQILSVPD

Enzyme Prediction     

No EC number prediction in MGYG000002242_00127.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH18	103	308	3e-35	0.6824324324324325

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd02874	GH18_CFLE_spore_hydrolase	1.58e-41	31	311	8	310	Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858	YaaH	1.00e-36	101	318	191	422	Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
cd06549	GH18_trifunctional	4.03e-20	86	311	75	298	GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.
pfam00704	Glyco_hydro_18	8.29e-16	86	305	75	306	Glycosyl hydrolases family 18.
smart00636	Glyco_18	2.81e-14	113	305	105	333	Glyco_18 domain.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEB15386.1	1.30e-239	1	318	1	318
QQA00962.1	1.22e-106	20	318	40	336
QTQ11038.1	2.13e-101	23	318	131	422
QTQ17017.1	2.13e-101	23	318	131	422
QTQ14800.1	1.86e-100	23	318	100	391

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4Q6T_A	3.53e-21	89	315	86	336	Thecrystal structure of a class V chitininase from Pseudomonas fluorescens Pf-5 [Pseudomonas protegens Pf-5]
5JH8_A	5.52e-20	116	314	105	310	Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
4S3K_A	2.14e-19	105	315	204	424	ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
3CZ8_A	2.75e-19	112	303	108	308	ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4S3J_A	2.70e-17	101	314	195	421	Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O05495	4.26e-19	112	303	200	400	Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
P0DPJ9	7.98e-17	101	314	194	420	Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1
P37531	8.02e-17	101	315	192	420	Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
Q9K3E4	6.58e-16	101	314	194	420	Cortical fragment-lytic enzyme OS=Bacillus cereus OX=1396 GN=sleL PE=1 SV=1
O31682	1.17e-15	88	231	72	214	Putative glycosylase YkvQ OS=Bacillus subtilis (strain 168) OX=224308 GN=ykvQ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000552	0.270221	0.728728	0.000151	0.000181	0.000151

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002242_00127.