Species | CAG-841 sp002479075 | |||||||||||
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Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; CAG-841; CAG-841 sp002479075 | |||||||||||
CAZyme ID | MGYG000002261_01053 | |||||||||||
CAZy Family | GH23 | |||||||||||
CAZyme Description | Membrane-bound lytic murein transglycosylase C | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 1130; End: 2260 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH23 | 63 | 200 | 1.3e-30 | 0.8 |
GH23 | 235 | 363 | 1.5e-21 | 0.8 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd16896 | LT_Slt70-like | 2.31e-59 | 44 | 198 | 1 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd13401 | Slt70-like | 5.19e-49 | 43 | 202 | 2 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
cd00254 | LT-like | 2.09e-38 | 62 | 197 | 1 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
COG0741 | MltE | 8.83e-36 | 22 | 208 | 114 | 292 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
cd16896 | LT_Slt70-like | 3.35e-34 | 221 | 361 | 6 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ACL76418.1 | 2.86e-37 | 14 | 207 | 13 | 195 |
CDZ23581.1 | 8.57e-34 | 38 | 207 | 32 | 192 |
AEY66639.1 | 9.32e-34 | 14 | 207 | 13 | 195 |
AXU49364.1 | 1.34e-33 | 23 | 205 | 11 | 180 |
AWH80563.1 | 1.34e-33 | 23 | 205 | 11 | 180 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1QSA_A | 3.58e-17 | 43 | 205 | 449 | 604 | CrystalStructure Of The 70 Kda Soluble Lytic Transglycosylase Slt70 From Escherichia Coli At 1.65 Angstroms Resolution [Escherichia coli],1QTE_A Crystal Structure Of The 70 Kda Soluble Lytic Transglycosylase Slt70 From Escherichia Coli At 1.90 A Resolution In Complex With A 1,6- Anhydromurotripeptide [Escherichia coli] |
1SLY_A | 6.58e-16 | 43 | 205 | 449 | 604 | ComplexOf The 70-Kda Soluble Lytic Transglycosylase With Bulgecin A [Escherichia coli] |
6FBT_A | 1.16e-15 | 59 | 195 | 461 | 588 | ChainA, Lytic murein transglycosylase [Pseudomonas aeruginosa] |
5OHU_A | 1.21e-15 | 59 | 195 | 490 | 617 | TheX-ray Structure of Lytic Transglycosylase Slt from Pseudomonas aeruginosa [Pseudomonas aeruginosa] |
5MPQ_A | 2.67e-15 | 43 | 204 | 412 | 560 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
O31608 | 1.08e-20 | 51 | 196 | 64 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
O31976 | 2.82e-18 | 43 | 196 | 1418 | 1541 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
O64046 | 2.82e-18 | 43 | 196 | 1418 | 1541 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
P39434 | 1.95e-17 | 43 | 213 | 476 | 639 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
P0AGC4 | 2.02e-16 | 43 | 205 | 476 | 631 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.855949 | 0.123865 | 0.011411 | 0.000764 | 0.000592 | 0.007431 |
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