CAZyme Information: MGYG000002275_02981

Basic Information

• Species: Paraprevotella sp003477995
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella sp003477995
• CAZyme ID: MGYG000002275_02981
• CAZy Family: GH84
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1387		154706.78	4.6776

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002275	3751567	Isolate	China	Asia

• Gene Location: Start: 1743; End: 5906 Strand: +

Full Sequence      

MALAWTCSIGSMQAQQVTVSPLPQNISWGSKAFDQGFSYTLTGEQDADADAVRVLKNKLK
TGNGTNVNIIIGERGDAAVKAYETNIPNKKEGYYLKVEGDKVIIAGNDESGTFYGVQTFL
QIASQPEVMQATVTDYPDVIDRGVVEGFYGNPWSTTDRKRQFEFYGENKMNVYIYGPKDD
PYHRAKWREPYPAAEAAVLKELIQSAHENKVQFVWALHPGNDIKWNDTDRQNVVKKLELM
YEMGVRAFSLFFDDIGGEGTDPTNQANLINYVTENFIKAHPELPPLIFCPTQYNRSWSSG
DYLNILGSKSDKDARIMWTGNSVVDMINKSDMDWINAQIQRNAYIWLNYPTNDYCIDRML
MGPTYGNDKNIAEQLSGFTANPSEYAEASKVSLYSIADYTWNMENYDENASWERAIKYLM
PDHAAAFKVFCENNIDLGSTYHGLRREGESKRFAEAIKVFQEATANGFNKEAFDAIKPMF
DEFVNSCNELLDPQVQENDPLAKELVAWFQVMKLMGERGQKMCSLYASIADNKPEEFINT
YKEMVQLEAEQKAIRSRDFEGSIKSPNPTVAAEVVAPFMKQYTNLLIAEYKKHYTDGWEN
FPAVLLNDGKYYIKYNGKFLTNVSGSKYPTFVANEDDINPQRQEWVISMDYSTNRYKIVN
AQDNRYLNEKGEFTVNETTNPYESAWHSYNITRLNGKYAIQNAGSAGDKYWTANATRVST
GSVSAYNPENFIFELVPLDEEAITYPVIVSGGSYHIINPTDGSYLTNNTGNNNPKFEAKK
EKDPQNTQSWTFTLVPATGRYKIVSAADNRNLNEMGQFGTAYDDNWNTFKMQELGGLFFI
QCAGSAGNNFWSIENNAISKGNKTEGESYIFKIDQAPEAPMDEEATLVFYKQGLVTDPNQ
IADGDYVVLQNVNTGNANRQGYLYYQDDTKFLTFLAGYYQTELTDMKSAFPDKYVFQVEK
NAQGLSFKNVTAKKYIPNNVASGAYAPTENADNSKFTLEASAQVSMAWNIKSAANGKYIN
GEPGYPVVWSDGHPIKIYKVAESAAPADVEGNGWFRIQTTDGQSGLRMQLGDADGEELVW
MKGMTGAAGDEALWSLQESPEVAGRYALVNKKNDKGSVNWQNDKTHEALINQFDYSQDHK
DFGIYVKTQTTEVLPSWVMYRINGGNSVMRFLNHQGAYLKEAEDPSQTGKLWKMIPAASL
ELTANGYAVGAFSAPVATIVPQNVWVYAATASTDQEVTLSRLEGKILPANTPVLLVANNA
GNYEMSPTTGTDQVITPGTNLLKSTTSGKILAPAQSMTLSISDEEACMAPVTAGSPLKGY
SVYLPQNGQSVKKALVFDELPPVTGILSPEDTASQGNGKIYDLSGREVSKPTKGVYIRNG
QKFIVNQ

Enzyme Prediction     

No EC number prediction in MGYG000002275_02981.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH84	142	431	1e-106	0.9932203389830508

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07555	NAGidase	4.48e-156	142	430	1	293	beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838	Glyco_hydro_20b	5.80e-15	21	125	6	110	Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QFQ13183.1	2.38e-257	4	738	16	735
QUB43766.1	6.08e-174	71	737	73	736
QRM68690.1	5.34e-165	4	592	11	602
QCQ48131.1	5.34e-165	4	592	11	602
QLK80951.1	5.34e-165	4	592	11	602

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2VVN_A	7.99e-156	14	579	21	586	BtGH84in complex with NH-Butylthiazoline [Bacteroides thetaiotaomicron VPI-5482],2VVN_B BtGH84 in complex with NH-Butylthiazoline [Bacteroides thetaiotaomicron VPI-5482],2VVS_A BtGH84 structure in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],2X0H_A BtGH84 Michaelis complex [Bacteroides thetaiotaomicron VPI-5482],2X0H_B BtGH84 Michaelis complex [Bacteroides thetaiotaomicron VPI-5482],4AIS_A A complex structure of BtGH84 [Bacteroides thetaiotaomicron VPI-5482],4AIS_B A complex structure of BtGH84 [Bacteroides thetaiotaomicron VPI-5482],7OU8_AAA Chain AAA, O-GlcNAcase BT_4395 [Bacteroides thetaiotaomicron VPI-5482],7OU8_BBB Chain BBB, O-GlcNAcase BT_4395 [Bacteroides thetaiotaomicron VPI-5482]
7K41_A	1.27e-155	14	579	3	568	ChainA, O-GlcNAcase BT_4395 [Escherichia coli K-12]
2J47_A	1.61e-155	15	579	1	565	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor [Bacteroides thetaiotaomicron VPI-5482],2W4X_A BtGH84 in complex with STZ [Bacteroides thetaiotaomicron VPI-5482],2W66_A BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W66_B BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W67_A BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2W67_B BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2WCA_A BtGH84 in complex with n-butyl pugnac [Bacteroides thetaiotaomicron VPI-5482],2XJ7_A BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XJ7_B BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XM1_A BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM1_B BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM2_A BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],2XM2_B BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],4UR9_A Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],4UR9_B Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],5FKY_A Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FKY_B Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FL0_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL0_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron]
2CHO_A	1.61e-155	15	579	1	565	Bacteroidesthetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482],2CHO_B Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482]
2WZI_A	4.26e-155	14	579	21	586	BtGH84D243N in complex with 5F-oxazoline [Bacteroides thetaiotaomicron VPI-5482],2WZI_B BtGH84 D243N in complex with 5F-oxazoline [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q89ZI2	4.38e-155	14	579	21	586	O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q0TR53	2.40e-97	19	490	46	539	O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08	6.09e-97	19	490	46	539	O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
P26831	3.81e-48	19	426	41	488	Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
O60502	7.69e-36	143	405	63	335	Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.851078	0.147784	0.000560	0.000262	0.000124	0.000212

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002275_02981.