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CAZyme Information: MGYG000002281_00184

You are here: Home > Sequence: MGYG000002281_00184

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides faecis
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides faecis
CAZyme ID MGYG000002281_00184
CAZy Family GH38
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
849 97136.06 6.9809
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002281 6145961 Isolate China Asia
Gene Location Start: 236564;  End: 239113  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002281_00184.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH38 12 265 2.4e-33 0.9219330855018587

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0383 AMS1 1.55e-23 84 848 273 943
Alpha-mannosidase [Carbohydrate transport and metabolism].
pfam01074 Glyco_hydro_38 1.32e-14 46 189 32 172
Glycosyl hydrolases family 38 N-terminal domain. Glycosyl hydrolases are key enzymes of carbohydrate metabolism.
PRK09819 PRK09819 7.92e-14 387 826 376 859
mannosylglycerate hydrolase.
cd10789 GH38N_AMII_ER_cytosolic 7.96e-12 46 189 32 171
N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38). The subfamily is represented by Saccharomyces cerevisiae vacuolar alpha-mannosidase Ams1, rat ER/cytosolic alpha-mannosidase Man2C1, and similar proteins. Members in this family share high sequence similarity. None of them have any classical signal sequence or membrane spanning domains, which are typical of sorting or targeting signals. Ams1 functions as a second resident vacuolar hydrolase in S. cerevisiae. It aids in recycling macromolecular components of the cell through hydrolysis of terminal, non-reducing alpha-d-mannose residues. Ams1 utilizes both the cytoplasm to vacuole targeting (Cvt, nutrient-rich conditions) and autophagic (starvation conditions) pathways for biosynthetic delivery to the vacuole. Man2C1is involved in oligosaccharide catabolism in both the ER and cytosol. It can catalyze the cobalt-dependent cleavage of alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues. Members in this family are retaining glycosyl hydrolases of family GH38 that employs a two-step mechanism involving the formation of a covalent glycosyl-enzyme complex. Two carboxylic acids positioned within the active site act in concert: one as a catalytic nucleophile and the other as a general acid/base catalyst.
smart00872 Alpha-mann_mid 6.91e-09 297 344 14 62
Alpha mannosidase, middle domain. Members of this entry belong to the glycosyl hydrolase family 38, This domain, which is found in the central region adopts a structure consisting of three alpha helices, in an immunoglobulin/albumin-binding domain-like fold. The domain is predominantly found in the enzyme alpha-mannosidase.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QQA07855.1 0.0 1 849 1 849
QUT69752.1 0.0 1 849 1 849
AAO79177.1 0.0 1 849 1 849
QMW86426.1 0.0 1 849 1 849
ALJ43681.1 0.0 1 849 1 849

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q54K67 1.15e-10 75 844 315 1082
Alpha-mannosidase G OS=Dictyostelium discoideum OX=44689 GN=manG PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000196 0.999209 0.000150 0.000138 0.000133 0.000129

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002281_00184.