CAZyme Information: MGYG000002281_01152

Basic Information

• Species: Bacteroides faecis
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides faecis
• CAZyme ID: MGYG000002281_01152
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
982		111210.49	6.7832

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002281	6145961	Isolate	China	Asia

• Gene Location: Start: 385070; End: 388018 Strand: -

Full Sequence      

MRILFLLVILSVASALQSQVVVKENMIQSKSAFPLVTSNTKAAVVYDADDYLVVQKTAEL
FVADVESVTGKQLRLTDTVKGDKEIIVVGTIEKNRLIRQLAEKGKLDISPLEGAWERYLI
QTVSRPFPGVSKALVIAGSDRRGAAYGLFSLSEMMGVSPWYWWADVPAKKHKTLYIDAPA
TLSKTPSVKYRGIFLNDEDWGLKPWAAKTFEKERGNIGPRTYAKICELLLRLKANHLAPA
MHPVSTAFYKIPENKLVADTFAIVMGSSHCEPLLLNTASEWDSKTMGPWDYNKNKDKINE
VLSNRVKENCAYENVYTLALRGLHDAAMGGGDVPMREKVKMLESALNAQRDIIARHIDKP
VETIPQAFTPYKEVLEIYSNGLELPDDVTIIWADDNFGYMKRLSGPHEQKRSGRAGVYYH
ISYLGVPHSYLWYSTTPPALMYEELRKAYDTTADRVWLANCGDLKGAETQISLFLDMAYD
IDQFNAGNVATYPARWLAKMFGEQYYDLFQDITCSHINLAFSRKPEYMGWGYWNNYWGGG
EKRTDTEFSFANYNEAERRLTEYSRIGKKAENLLAALDEESRPAFYQLLYYPVKGAELMN
HMTIKGQFYRQYVRQQRAAADRLKAQVKCYHDSLEIITDGYNSLLDGKWKYMMSLKQNYD
GTSSYFMIPLMEEEYTPVGAPRLAVQAESENLDKGGMSFHALPVFSTYARKSYWIDIYNQ
GTGELNWSVAPSDDWILISQKSGKTSTENRIHISVNWDKVPVGEKVKGQIDITSGNQKES
VLVSVFNPESPARDELQGLYVEENGYISIPAADFHRKFESNDIQMNILAGLGFEGRSLQL
GNPTAPLQMYRAGDVPRVEYDFYTFNAGIYDVYTYVLPTFPLHAERDYKLPEHTNSDTKY
SVRIDDGSISTPSTSAIEYSQIWYDSVLKNCRVNKSTLYVKKPGRHTLQIRCGDPGVVIQ
KIVIDLGGLKRSYLGPQSTICN

Enzyme Prediction     

No EC number prediction in MGYG000002281_01152.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	31	659	2.1e-227	0.8278335724533716

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	1.59e-164	184	526	1	333	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	3.02e-56	800	976	2	170	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	3.91e-06	65	151	44	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).
pfam19190	BACON_2	3.00e-05	719	785	24	88	Viral BACON domain. This family represents a distinct class of BACON domains found in crAss-like phages, the most common viral family in the human gut, in which they are found in tail fiber genes. This suggests they may play a role in phage-host interactions.
cd14948	BACON	1.43e-04	726	784	27	81	Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCA48102.1	0.0	1	982	1	982
QUT69262.1	0.0	1	982	1	982
QUT41413.1	0.0	1	982	1	982
QMW85894.1	0.0	1	982	1	982
AAO78620.1	0.0	1	982	1	982

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4ZMH_A	1.27e-149	42	976	23	930	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
5BY3_A	4.87e-124	38	656	24	618	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4C90_A	1.16e-106	33	656	44	643	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
6NPS_A	2.33e-106	35	979	12	963	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]
7PUG_A	8.04e-98	33	657	17	629	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000235	0.999167	0.000159	0.000143	0.000134	0.000131

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002281_01152.