CAZyme Information: MGYG000002284_00377

Basic Information

• Species: Megamonas funiformis
• Lineage: Bacteria; Firmicutes_C; Negativicutes; Selenomonadales; Selenomonadaceae; Megamonas; Megamonas funiformis
• CAZyme ID: MGYG000002284_00377
• CAZy Family: GH36
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
548	MGYG000002284_3|CGC1	63419.99	5.0603

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002284	2244659	Isolate	China	Asia

• Gene Location: Start: 42959; End: 44605 Strand: -

Full Sequence      

MLKNILKINRPDFIELTTETKTVTSKWKNDDYNLDDINVNLNQDNEHLAIFLTAQTSKVK
WIKLRWNNLSWDKNVRFLGDAWERGYGDMEWKGMNPNRFMPWYFCAKSEAKSICYGVKVR
PSAMCFWQVDSLGMTLFLDVRCGGSGVNLKGRVIKLADVIACEMRDCTSFEAMQEFCGQM
CEDPILPKYSVYGSNNWYYAYGKSSESEILADCDYILNLTKDIENKPYMVIDDCWQEHHR
LNEYNGGPWTKGNEKFPDMKALAEKLVQKGVRPGIWVRLLLNEDENIKNEWRLSHNNCID
PTNPEALNYIKEDIKRICNWGYTLIKHDFSTFDLFGKWGFQMSPLVTDDGWHFYDDSLTS
AEVVKLLYKAILDASVEASNGETLILGCNTIGHLGAGYMHINRTGDDTSGVIWERTRFMG
VNTLAFRLPQHGKFYEIDADCVGIDGGISWSMNKQWADVLAKSGTPLFISVRPNILDETE
KQELHEILKVASKQEHHVIPVDWEETTCPEHWQDKDHDIDCKYQWFEETGLKFNPNTIRY
QTFLAMVE

Enzyme Prediction     

No EC number prediction in MGYG000002284_00377.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd14791	GH36	1.05e-40	191	493	3	299	glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
cd14792	GH27	2.94e-10	196	329	6	124	glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.
COG3345	GalA	4.25e-06	184	342	286	446	Alpha-galactosidase [Carbohydrate transport and metabolism].
cd06592	GH31_NET37	4.74e-06	216	318	20	139	glucosidase NET37. NET37 (also known as KIAA1161) is a human lamina-associated nuclear envelope transmembrane protein. A member of the glycosyl hydrolase family 31 (GH31) , it has been shown to be required for myogenic differentiation of C2C12 cells. Related proteins are found in eukaryotes and prokaryotes. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.
cd14790	GH_D	1.72e-04	197	329	8	107	Glycoside hydrolases, clan D. This group of glycosyl hydrolase families is comprised of glycosyl hydrolase family 31 (GH31), family 36 (GH36), and family 27 (GH27). These structurally and mechanistically related protein families are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. They have a wide range of functions including alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase, alpha-N-acetylgalactosaminidase, stachyose synthase, raffinose synthase, and alpha-1,4-glucan lyase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BDA09953.1	0.0	1	548	1	548
QIB59833.1	0.0	1	548	1	548
SNU96820.1	4.15e-301	1	547	1	544
CBL06135.1	2.04e-245	229	548	1	320
CBL19648.1	6.28e-243	7	530	27	544

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000028	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002284_00377.