CAZyme Information: MGYG000002292_02025

Basic Information

• Species: TF01-11 sp003529475
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; TF01-11; TF01-11 sp003529475
• CAZyme ID: MGYG000002292_02025
• CAZy Family: GT2
• CAZyme Description: Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
891	MGYG000002292_12|CGC1	105717.5	8.0555

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002292	3137432	Isolate	China	Asia

• Gene Location: Start: 16184; End: 18859 Strand: +

Full Sequence      

MENSRFKFSVIIPVYNVENYLEETIQSVIHQTIGFKKNIQIILVNDGSPDDSGKICEKYQ
REYPDNIVYVEQKNAGVSAARNNGLKYAEGEIINFLDSDDKWGKTAFKRAYRFFQKYGNE
IDIVAGRIKYFEMKDNYHVLDYKFDNDKLVDIQKDHEYIQLSMATTFVRAEALKGRQFDS
RIRYGEDCLLINTILFDKCKYGVIRDCVYYYRMRNTGTSAMQNTISQKTWYFDTEKLVFQ
HLLEMSKEKFGKPIKYVQYLIMYDMKWRLRTVVPSGVLTEEEKKQYLELLHVILQDIDDD
MIATQKNCLSLHYLLAYQLKYQKDCRDEITFDGGLVCFHGQRLTHMARRRFLTLDFVDIK
DNVLEITGQADFWIYEDDYKILFEDQNGTEYYPTYYPLPFRTRHGLLGDYGDVRGYHVSI
PLAGVRRLRAVFEYKNGERCYMMIGYGKFCQLTHAMDSSYGLYDRHILRAKGKTIYVQKK
TRKRYRKCERRYCLELVKKGYFKECFYRYATRVFRKIHSNKKIWLLSDRINLARDNGEAL
FQYLNRIDTGNVDVYFDISKKCSDYERMKQIGKVVPHGSFRYCMYFLSADKIISAHIDEY
VINAFGVKRDYLKNLFRFDFVFLQHGLTKDDLSGWVNRFNKNISLFVTAAKPEYQSIVDG
NYFYTDKEVKLTGFPRFDNLVADKTKKQIIILPTWRKQLANSIDQKTGQRIYNDTFKNSA
FFKFYDRLIQDERLLDCMREHGYTGKFCLHVNHMEQIGDYHGNDVIQIHEGALNYQKEFV
ENALMVTDYSSVAFDFAYMKKSLVYAQFDREAFFEGQTYDEGYFNYETDGFGPVCYDYET
TVQSIIDAIKRDCEMSEEYKKRVDNFYYKTDTDNCKRVYEAILAIDQNKEA

Enzyme Prediction     

No EC number prediction in MGYG000002292_02025.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	9	139	1.4e-31	0.7470588235294118

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam04464	Glyphos_transf	1.41e-33	521	883	5	359	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.
cd00761	Glyco_tranf_GTA_type	3.14e-30	10	126	1	113	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	6.69e-30	9	138	1	126	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
PRK10073	PRK10073	5.08e-25	1	101	1	97	putative glycosyl transferase; Provisional
COG1887	TagB	2.38e-23	520	886	25	388	CDP-glycerol glycerophosphotransferase, TagB/SpsB family [Cell wall/membrane/envelope biogenesis, Lipid transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASB62640.1	4.45e-204	1	888	1	887
QAW34904.1	4.45e-204	1	888	1	887
ASZ63009.1	4.45e-204	1	888	1	887
AUS11687.1	6.28e-204	1	888	1	887
QFY83675.1	1.25e-203	1	888	1	887

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5HEA_A	9.41e-23	1	219	1	223	CgTstructure in hexamer [Streptococcus parasanguinis FW213],5HEA_B CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEA_C CgT structure in hexamer [Streptococcus parasanguinis FW213],5HEC_A CgT structure in dimer [Streptococcus parasanguinis FW213],5HEC_B CgT structure in dimer [Streptococcus parasanguinis FW213]
3BCV_A	9.96e-23	7	117	6	112	Crystalstructure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343],3BCV_B Crystal structure of a putative glycosyltransferase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]
5TZE_C	3.83e-18	7	316	2	306	Crystalstructure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZE_E Crystal structure of S. aureus TarS in complex with UDP-GlcNAc [Staphylococcus aureus],5TZI_C Crystal structure of S. aureus TarS 1-349 [Staphylococcus aureus],5TZJ_A Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZJ_C Crystal structure of S. aureus TarS 1-349 in complex with UDP-GlcNAc [Staphylococcus aureus],5TZK_C Crystal structure of S. aureus TarS 1-349 in complex with UDP [Staphylococcus aureus]
5TZ8_A	1.44e-17	7	316	2	306	Crystalstructure of S. aureus TarS [Staphylococcus aureus],5TZ8_B Crystal structure of S. aureus TarS [Staphylococcus aureus],5TZ8_C Crystal structure of S. aureus TarS [Staphylococcus aureus]
2Z87_A	2.61e-10	9	100	377	464	Crystalstructure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GalNAc and UDP [Escherichia coli],2Z87_B Crystal structure of chondroitin polymerase from Escherichia coli strain K4 (K4CP) complexed with UDP-GalNAc and UDP [Escherichia coli]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P46918	1.29e-186	6	891	8	899	Minor teichoic acid biosynthesis protein GgaB OS=Bacillus subtilis (strain 168) OX=224308 GN=ggaB PE=3 SV=1
P46917	3.00e-46	8	368	2	355	Minor teichoic acid biosynthesis protein GgaA OS=Bacillus subtilis (strain 168) OX=224308 GN=ggaA PE=3 SV=1
A0A0H2URH7	1.14e-24	7	221	6	225	Glycosyltransferase GlyA OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=glyA PE=3 SV=1
E0U4V7	5.07e-20	7	378	2	388	Poly(ribitol-phosphate) beta-glucosyltransferase OS=Bacillus spizizenii (strain ATCC 23059 / NRRL B-14472 / W23) OX=655816 GN=tarQ PE=1 SV=1
P71059	5.64e-20	9	212	6	212	Uncharacterized glycosyltransferase EpsJ OS=Bacillus subtilis (strain 168) OX=224308 GN=epsJ PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000029	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002292_02025.