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CAZyme Information: MGYG000002306_02041

You are here: Home > Sequence: MGYG000002306_02041

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mycobacterium avium
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium avium
CAZyme ID MGYG000002306_02041
CAZy Family GT53
CAZyme Description putative arabinosyltransferase B
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1065 114626.9 9.3542
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002306 4669710 Isolate Australia Oceania
Gene Location Start: 2192;  End: 5389  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT53 11 1063 0 0.998093422306959

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 200 657 1 458
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 0.0 689 1062 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 9.31e-69 38 196 2 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AYQ68941.1 0.0 1 1065 1 1065
ASE12830.1 0.0 1 1065 1 1065
AJK76698.1 0.0 1 1065 1 1065
AJK80911.1 0.0 1 1065 1 1065
QQW57563.1 0.0 1 1065 1 1065

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6X0O_A 0.0 9 1065 22 1082
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BVC_B 0.0 9 1065 22 1082
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]
7BVF_B 0.0 11 1065 24 1098
Cryo-EMstructure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycobacterium tuberculosis H37Rv]
7BWR_A 0.0 9 1065 22 1082
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
7BVE_A 1.85e-306 7 1064 9 1074
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WNL7 0.0 11 1065 24 1098
Probable arabinosyltransferase B OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embB PE=1 SV=1
Q50395 0.0 9 1065 22 1082
Probable arabinosyltransferase B OS=Mycolicibacterium smegmatis OX=1772 GN=embB PE=3 SV=3
Q7TVN3 0.0 11 1065 24 1098
Probable arabinosyltransferase B OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embB PE=3 SV=1
P9WNL6 0.0 11 1065 24 1098
Probable arabinosyltransferase B OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embB PE=3 SV=1
Q9CDA9 0.0 5 1065 16 1083
Probable arabinosyltransferase B OS=Mycobacterium leprae (strain TN) OX=272631 GN=embB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.991481 0.008462 0.000020 0.000013 0.000011 0.000055

TMHMM  Annotations      download full data without filtering help

start end
15 37
204 226
241 263
394 413
417 436
441 463
510 527
539 556
566 588
595 617
632 654
667 689