You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000002306_02042
You are here: Home > Sequence: MGYG000002306_02042
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Mycobacterium avium | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium avium | |||||||||||
| CAZyme ID | MGYG000002306_02042 | |||||||||||
| CAZy Family | GT53 | |||||||||||
| CAZyme Description | putative arabinosyltransferase A | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 5386; End: 7251 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT53 | 1 | 618 | 2.3e-256 | 0.5681601525262154 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam14896 | Arabino_trans_C | 0.0 | 228 | 618 | 1 | 384 | EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate. |
| pfam04602 | Arabinose_trans | 1.37e-68 | 2 | 192 | 270 | 459 | Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AZA68862.1 | 0.0 | 1 | 621 | 488 | 1108 |
| AYQ68942.1 | 0.0 | 1 | 621 | 488 | 1108 |
| AXO25250.1 | 0.0 | 1 | 621 | 488 | 1108 |
| QPM69808.1 | 0.0 | 1 | 621 | 488 | 1108 |
| AYQ77640.1 | 0.0 | 1 | 621 | 488 | 1108 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7BVC_A | 0.0 | 1 | 621 | 469 | 1088 | Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_A Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155] |
| 7BVF_A | 0.0 | 1 | 621 | 484 | 1102 | Cryo-EMstructure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycobacterium tuberculosis H37Rv] |
| 7BVE_A | 1.82e-144 | 1 | 618 | 479 | 1072 | Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155] |
| 7BVH_A | 3.45e-144 | 1 | 618 | 492 | 1085 | Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155] |
| 7BWR_A | 1.09e-141 | 1 | 621 | 485 | 1082 | Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q50394 | 0.0 | 1 | 621 | 474 | 1092 | Probable arabinosyltransferase A OS=Mycolicibacterium smegmatis OX=1772 GN=embA PE=3 SV=2 |
| P9WNL8 | 0.0 | 1 | 621 | 476 | 1094 | Probable arabinosyltransferase A OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embA PE=3 SV=1 |
| P9WNL9 | 0.0 | 1 | 621 | 476 | 1094 | Probable arabinosyltransferase A OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embA PE=1 SV=1 |
| P71485 | 0.0 | 1 | 621 | 488 | 1108 | Probable arabinosyltransferase A OS=Mycobacterium avium OX=1764 GN=embA PE=3 SV=1 |
| Q9CDA8 | 0.0 | 1 | 621 | 487 | 1111 | Probable arabinosyltransferase A OS=Mycobacterium leprae (strain TN) OX=272631 GN=embA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999970 | 0.000067 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 39 | 61 |
| 68 | 90 |
| 100 | 122 |
| 129 | 151 |
| 166 | 188 |
| 209 | 231 |