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CAZyme Information: MGYG000002306_04226
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Mycobacterium avium | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium avium | |||||||||||
| CAZyme ID | MGYG000002306_04226 | |||||||||||
| CAZy Family | GT2 | |||||||||||
| CAZyme Description | D-alanine--poly(phosphoribitol) ligase subunit 1 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1403; End: 7360 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12316 | PRK12316 | 0.0 | 1 | 1536 | 2095 | 3633 | peptide synthase; Provisional |
| cd05930 | A_NRPS | 0.0 | 967 | 1442 | 1 | 444 | The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions. |
| PRK12467 | PRK12467 | 0.0 | 1 | 1536 | 604 | 2175 | peptide synthase; Provisional |
| PRK12467 | PRK12467 | 0.0 | 460 | 1536 | 23 | 1106 | peptide synthase; Provisional |
| PRK05691 | PRK05691 | 0.0 | 1 | 1517 | 111 | 1695 | peptide synthase; Validated |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QND46664.1 | 4.11e-293 | 1 | 1537 | 1101 | 2675 |
| ACX49739.1 | 4.90e-208 | 46 | 1218 | 618 | 1837 |
| BAY90071.1 | 1.33e-191 | 393 | 1524 | 2131 | 3280 |
| BAY30132.1 | 1.35e-191 | 393 | 1527 | 2142 | 3294 |
| BAZ00088.1 | 1.52e-189 | 393 | 1527 | 2140 | 3292 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5U89_A | 1.46e-223 | 1 | 936 | 116 | 1070 | Crystalstructure of a cross-module fragment from the dimodular NRPS DhbF [Geobacillus sp. Y4.1MC1] |
| 5MSO_A | 7.16e-217 | 920 | 1985 | 12 | 1174 | Structureof the R domain of carboxylic acid reductase (CAR) from Mycobacterium marinum in complex with NADP [Mycobacterium marinum M],5MSU_A Structure of the R domain of carboxylic acid reductase (CAR) from Mycobacterium marinum in complex with NADP, P21 form [Mycobacterium marinum M],5MSU_B Structure of the R domain of carboxylic acid reductase (CAR) from Mycobacterium marinum in complex with NADP, P21 form [Mycobacterium marinum M],5MSU_C Structure of the R domain of carboxylic acid reductase (CAR) from Mycobacterium marinum in complex with NADP, P21 form [Mycobacterium marinum M] |
| 4U5Q_A | 1.51e-208 | 1543 | 1985 | 35 | 478 | Highresolution crystal structure of reductase (R) domain of nonribosomal peptide synthetase from Mycobacterium tuberculosis [Mycobacterium tuberculosis H37Rv],4U5Q_B High resolution crystal structure of reductase (R) domain of nonribosomal peptide synthetase from Mycobacterium tuberculosis [Mycobacterium tuberculosis H37Rv] |
| 4DQV_A | 6.40e-205 | 1543 | 1985 | 35 | 478 | ChainA, PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) [Mycobacterium tuberculosis] |
| 6P1J_A | 5.94e-201 | 485 | 1442 | 7 | 964 | Thestructure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae],6P1J_B The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module [Eleftheria terrae] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q70LM4 | 0.0 | 45 | 1906 | 3186 | 5008 | Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis OX=54914 GN=lgrD PE=1 SV=1 |
| P45745 | 0.0 | 1 | 1527 | 550 | 2107 | Dimodular nonribosomal peptide synthase OS=Bacillus subtilis (strain 168) OX=224308 GN=dhbF PE=1 SV=4 |
| Q70LM5 | 1.37e-285 | 48 | 1504 | 3205 | 4669 | Linear gramicidin synthase subunit C OS=Brevibacillus parabrevis OX=54914 GN=lgrC PE=3 SV=1 |
| Q70LM6 | 7.19e-274 | 29 | 1525 | 3162 | 4669 | Linear gramicidin synthase subunit B OS=Brevibacillus parabrevis OX=54914 GN=lgrB PE=1 SV=1 |
| P0DUV3 | 1.33e-262 | 50 | 1524 | 1636 | 3120 | Malpicyclin synthetase OS=Mortierella alpina OX=64518 GN=mpcA PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000049 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |