Species | Vibrio cholerae | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Vibrionaceae; Vibrio; Vibrio cholerae | |||||||||||
CAZyme ID | MGYG000002311_02585 | |||||||||||
CAZy Family | GT9 | |||||||||||
CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 2863450; End: 2864487 Strand: + |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG0859 | RfaF | 6.24e-86 | 1 | 341 | 1 | 331 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
cd03789 | GT9_LPS_heptosyltransferase | 3.21e-60 | 3 | 335 | 1 | 269 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
pfam01075 | Glyco_transf_9 | 3.52e-17 | 71 | 308 | 4 | 227 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
PRK10422 | PRK10422 | 8.08e-05 | 2 | 300 | 6 | 298 | lipopolysaccharide core biosynthesis protein; Provisional |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
SPM14626.1 | 5.01e-253 | 1 | 345 | 1 | 345 |
QHA23139.1 | 5.01e-253 | 1 | 345 | 1 | 345 |
AIT30890.1 | 5.01e-253 | 1 | 345 | 1 | 345 |
QJS82730.1 | 5.01e-253 | 1 | 345 | 1 | 345 |
APF81748.1 | 5.01e-253 | 1 | 345 | 1 | 345 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P44011 | 4.51e-129 | 1 | 343 | 1 | 339 | Putative glycosyltransferase HI_0523 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=HI_0523 PE=3 SV=2 |
Q9R9D5 | 3.07e-06 | 13 | 303 | 5 | 289 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000060 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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