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CAZyme Information: MGYG000002312_00020

You are here: Home > Sequence: MGYG000002312_00020

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Blautia_A sp000285855
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A sp000285855
CAZyme ID MGYG000002312_00020
CAZy Family GH42
CAZyme Description Beta-galactosidase BglY
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
674 MGYG000002312_1|CGC1 76959.16 5.3358
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002312 4168980 Isolate France Europe
Gene Location Start: 12436;  End: 14460  Strand: +

Full Sequence      Download help

MDFRTDRLLH  GGDYNPEQWL  KRPDILEKDI  DMLEESGCNV  VSLGIFSWST  LEPEEGVFHF60
GWLQEIIDKL  YKRGISTILA  TPSGARPKWM  ADKYPEVLRV  DETRHRALFG  FRHNHCYTSP120
VYREKVHIIN  KKLAQEVATH  PGVILWHISN  EYGGECHCPL  CQEAFRSWLK  EKYQTIENLN180
DQWCTTFWSH  TYNSFDQIES  PSKIGETQLH  ALNLDWKRFV  THQTADFIHH  EIAALREGGS240
TLPTTANLMH  YFGGLDYFKI  AKEIDVVSWD  TYPTWHKEAV  IDTAYDNGMC  HDLMRSLKGK300
PFFQMESCPT  STNWQSVSKL  KKPGMLFAQS  MQAIAHGGEG  ALYFQIRQSR  GASEKFHGAV360
IDHYGGNDTR  VFKEVSKVGA  TLKELKELAG  TTMSSPVAMI  YDWDSQWAME  DSQGPRNKGL420
HYLEAMLKFY  RGFRKQGVNV  DVIDMTCDLD  NYKVLALPMV  YMFKEGFAEK  VRAFVENGGV480
LVTSYWSGIA  DDTDRCYLEG  TPHGLMDVLG  IRSTEIDGLY  DWEENSFVPV  PGNELGLDKT540
YTCKYLCDLV  ELRGARTLMT  YGSDFYEGYS  CLTVNEYGRG  KAWYVAADAD  KEFYGDFLGK600
VLKDSVVSCG  IKEEIPDALE  ITVRENENVK  YYIYQNFGTE  SVELPVPEGE  VKWIYGNDSD660
KLKVYGLAVA  RVIV674

Enzyme Prediction      help

EC 3.2.1.23

CAZyme Signature Domains help

Created with Snap336710113416820223526930333737040443847150553957260664013383GH42
Family Start End Evalue family coverage
GH42 13 383 9.3e-152 0.9946091644204852

CDD Domains      download full data without filtering help

Created with Snap33671011341682022352693033373704044384715055395726066408649GanA13385Glyco_hydro_42397608Glyco_hydro_42M397607A4_beta-galactosidase_middle_domain619671Glyco_hydro_42C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1874 GanA 0.0 8 649 16 646
Beta-galactosidase GanA [Carbohydrate transport and metabolism].
pfam02449 Glyco_hydro_42 0.0 13 385 1 376
Beta-galactosidase. This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyzes the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.
pfam08532 Glyco_hydro_42M 8.45e-73 397 608 3 207
Beta-galactosidase trimerisation domain. This is non catalytic domain B of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. This domain is related to glutamine amidotransferase enzymes, but the catalytic residues are replaced by non functional amino acids. This domain is involved in trimerisation.
cd03143 A4_beta-galactosidase_middle_domain 2.70e-36 397 607 1 154
A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain. This group includes proteins similar to beta-galactosidase from Thermus thermophilus. Beta-Galactosidase hydrolyzes the beta-1,4-D-galactosidic linkage of lactose, as well as those of related chromogens, o-nitrophenyl-beta-D-galactopyranoside (ONP-Gal) and 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal). This A4 beta-galactosidase middle domain lacks the catalytic triad of typical GATase1 domains. The reactive Cys residue found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow in typical GATase1 domains is not conserved in this group.
pfam08533 Glyco_hydro_42C 0.002 619 671 2 57
Beta-galactosidase C-terminal domain. This domain is found at the C-terminus of beta-galactosidase enzymes that belong to the glycosyl hydrolase 42 family.

CAZyme Hits      help

Created with Snap33671011341682022352693033373704044384715055395726066404662QCU02956.1|GH422671QBE99588.1|GH424662CBL18491.1|GH422671QMW77254.1|GH422671QIB57823.1|GH42
Hit ID E-Value Query Start Query End Hit Start Hit End
QCU02956.1 1.72e-315 4 662 6 662
QBE99588.1 7.21e-315 2 671 4 672
CBL18491.1 1.99e-314 4 662 6 662
QMW77254.1 8.35e-314 2 671 4 672
QIB57823.1 8.35e-314 2 671 4 672

PDB Hits      download full data without filtering help

Created with Snap336710113416820223526930333737040443847150553957260664086585E9A_A86584OIF_A86584OJY_A86585DFA_A76423TTS_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5E9A_A 1.47e-246 8 658 39 691
Crystalstructure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_B Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_C Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_D Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_E Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3],5E9A_F Crystal structure analysis of the cold-adamped beta-galactosidase from Rahnella sp. R3 [Rahnella sp. R3]
4OIF_A 1.36e-209 8 658 15 666
3Dstructure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_B 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus],4OIF_C 3D structure of Gan42B, a GH42 beta-galactosidase from G. [Geobacillus stearothermophilus]
4OJY_A 1.41e-209 8 658 16 667
3Dstructure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],4OJY_B 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],4OJY_C 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus]
5DFA_A 1.09e-208 8 658 15 666
3Dstructure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],5DFA_B 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus],5DFA_C 3D structure of the E323A catalytic mutant of Gan42B, a GH42 beta-galactosidase from G. stearothermophilus [Geobacillus stearothermophilus]
3TTS_A 8.77e-175 7 642 8 640
ChainA, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_B Chain B, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_C Chain C, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_D Chain D, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_E Chain E, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTS_F Chain F, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_A Chain A, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_B Chain B, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_C Chain C, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_D Chain D, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_E Chain E, Beta-galactosidase [Niallia circulans subsp. alkalophilus],3TTY_F Chain F, Beta-galactosidase [Niallia circulans subsp. alkalophilus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap33671011341682022352693033373704044384715055395726066409669sp|C8WV58|BGAL_ALIAD4671sp|Q0TUR6|BGAL_CLOP18652sp|Q65CX4|BGAL2_BACLD8658sp|O07012|BGAL2_BACSU4644sp|Q09HN2|BGAL_PLASL
Hit ID E-Value Query Start Query End Hit Start Hit End Description
C8WV58 5.74e-255 9 669 15 680
Beta-galactosidase BglY OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / BCRC 14685 / JCM 5260 / KCTC 1825 / NBRC 15652 / NCIMB 11725 / NRRL B-14509 / 104-IA) OX=521098 GN=bglY PE=1 SV=1
Q0TUR6 9.53e-239 4 671 10 687
Beta-galactosidase Pbg OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=pbg PE=3 SV=1
Q65CX4 6.27e-207 8 652 1 646
Beta-galactosidase GalA OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) OX=279010 GN=lacA PE=1 SV=2
O07012 3.31e-201 8 658 1 652
Beta-galactosidase GanA OS=Bacillus subtilis (strain 168) OX=224308 GN=ganA PE=1 SV=2
Q09HN2 3.10e-189 4 644 5 645
Beta-galactosidase BgaP OS=Planococcus sp. (strain L4) OX=377621 GN=bgaP PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000063 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002312_00020.