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CAZyme Information: MGYG000002320_02202

You are here: Home > Sequence: MGYG000002320_02202

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Enterococcus_B lactis
Lineage Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus_B; Enterococcus_B lactis
CAZyme ID MGYG000002320_02202
CAZy Family PL8
CAZyme Description Xanthan lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
807 MGYG000002320_8|CGC4 91315.31 5.0822
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002320 3009500 Isolate Ireland Europe
Gene Location Start: 181203;  End: 183626  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002320_02202.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 418 685 1.6e-85 0.9884169884169884

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 0.0 36 755 1 692
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam08124 Lyase_8_N 1.71e-130 44 376 1 323
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02278 Lyase_8 2.49e-89 417 684 1 252
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 1.63e-11 700 764 1 67
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AWX48464.1 0.0 1 807 1 807
QIT62161.1 0.0 1 807 1 807
QIT57455.1 0.0 1 807 1 807
QZY25984.1 0.0 1 807 1 807
AYA35207.1 0.0 1 807 1 807

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 2.40e-110 35 755 4 695
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
2E22_A 6.61e-105 35 782 2 723
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 6.61e-105 35 782 2 723
ChainA, Xanthan lyase [Bacillus sp. GL1]
1J0M_A 3.52e-104 35 782 2 723
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
1X1H_A 9.60e-104 35 782 2 723
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 1.75e-102 35 782 27 748
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q54873 6.30e-95 57 725 312 960
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 4.70e-86 30 761 245 979
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q59801 1.53e-83 30 766 42 778
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
P0CZ01 8.89e-75 69 710 73 694
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.019563 0.975792 0.002867 0.001165 0.000327 0.000248

TMHMM  Annotations      download full data without filtering help

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