CAZyme Information: MGYG000002330_05096

Basic Information

• Species: Eisenbergiella tayi
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella tayi
• CAZyme ID: MGYG000002330_05096
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
822		95656.2	4.7301

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002330	7416064	Isolate	not provided	not provided

• Gene Location: Start: 20753; End: 23221 Strand: -

Full Sequence      

MLIQKLNENWQMCINNTEEFMPAAVPGSVYQDLLDNNKMEDPYYRDNELKALKIMENDFT
YVTCFDVPEDIREREEVLLHFDGIDTIGDIYLNGTLLGHVKNMHRIWEYSVKKLLKPEEN
ELKVVLHSPTRFIREAYEERPLEGSSDAMRGFPYLRKAHCMFGWDWGPRLPDAGIWREVE
LMAFDTARLDGVYITQKHEEGRVSLSVQVDVKRTGIKHTERFGREEKELEGLSWRIKVTD
PEGVPVFEGLCPEEAVIENPRLWWPNGYGSQPLYQVEVELLCDGCVLDSWSKKIGLRTMT
IHREKDEYGEQFAHEVNGVRIFAMGADYIPEDNILPRVKPERTYELLKQARDAHFNCIRV
WGGGNYPYDGFWDACDELGLVVWEDFMFACAIYDLTDEFEQDIIGEFIDNIKRIRHHASL
GLWCGNNEMEMFVKEGMWITRPKEKSDYVKIYEYIIPKVLKEYDPNTFYWPASPSSGGAF
DEPNDENRGDVHYWDVWHGNKPITEYRKFFFRYVSEFGFQSFPSLKTVETFTEPEDRNVF
SYVMEKHQRNQSANGKIMNYMEQTFLYPNDFDTTLYASQLLQAEAIRYGVEHFRRNRGRC
MGTVIWQLNDCWPVASWASIDYCGRWKALHYYAKRFFAPVMLSCAEEGILTQDTNPNAEP
YEVKKSIHLCVANETMEEQNLTVKWTLRNNRSEILRGGEEAVTAAPLSSVWLAKQDCMDA
DTYGDYVSYDCFRDGELISGGCVIFCAPKHYHFVDPKLTVTAEGDVLTVKANAYARGVEI
INEADDMLLEDNYFDMNAGERKIRILKGTPEGLKIRSVYNIR

Enzyme Prediction     

No EC number prediction in MGYG000002330_05096.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	707	3.4e-103	0.6808510638297872

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	4.17e-102	1	707	10	694	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam00703	Glyco_hydro_2	1.53e-12	187	297	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150	PRK10150	3.98e-11	7	428	31	417	beta-D-glucuronidase; Provisional
pfam17786	Mannosidase_ig	1.62e-09	667	750	3	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
PRK10340	ebgA	3.07e-08	61	428	113	449	cryptic beta-D-galactosidase subunit alpha; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEF82182.1	0.0	1	822	1	816
QBE97789.1	0.0	1	822	15	837
QIB54534.1	0.0	1	822	1	823
QMW79049.1	0.0	1	822	1	823
QJU13790.1	0.0	1	822	1	823

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7OP6_A	6.59e-161	3	821	10	842	ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2VJX_A	1.20e-160	3	819	8	838	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	1.27e-160	3	819	10	840	Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	1.74e-160	3	821	8	840	Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A	1.44e-158	3	819	8	838	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q0CCA0	3.95e-121	15	808	21	828	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
A1CGA8	1.68e-119	18	812	24	834	Beta-mannosidase B OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=mndB PE=3 SV=1
Q4WAH4	6.45e-119	6	812	9	834	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
B0YBU9	2.47e-118	6	812	9	834	Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mndB PE=3 SV=1
B8NW36	5.21e-116	18	663	24	682	Beta-mannosidase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000061	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002330_05096.