CAZyme Information: MGYG000002330_05272

Basic Information

• Species: Eisenbergiella tayi
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella tayi
• CAZyme ID: MGYG000002330_05272
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
824	MGYG000002330_158|CGC1	95536.91	4.7749

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002330	7416064	Isolate	not provided	not provided

• Gene Location: Start: 27; End: 2501 Strand: -

Full Sequence      

MRKKELDHGWMMRQNGTGEFLPAVVPGSVYTDLMANGKMEDPYYRDNEYQALEVISHDYE
YRVDFTAEAEIREEDEVLLRFDGIDTLADIWLNEVYLGKTNNMHRTWEFSVKSLLKEENT
LRAVLYSPTEFIARSYEEDPIIGCVDAMKGLPRLRKGHSMFGWDWGPRIPDAGIWRKVSL
LGVHKGRLESVSVTQTHEDGRVLLGFQPEILKCCEGGEKRAGAGDGFSCHITVTDPKGKQ
QDTRLEEDISEKGEIEIKEPCLWWPNGYGEQPLYTVCVQLWKDGELLDVWERRIGLRTMG
VSRRKDEFGEEFAHEVNGVRIFAMGADYIPEDNLLPRVNGERTRRLLEACRDAHFNVIRV
WGGGYYPDDFFYDICDELGLVVWQDFMFACCVYDLTEEFDRNIRAEFADNIRRIRHHASL
GLWCGNNEMEYFLEMDEKGWCLKPSQKSDYFKMFEYIIPQVLKELDPGTFYWPASPSSGG
GFDAPNDENRGDVHYWDVWHGGKPFTEYRKFFFRYLSEFGFQSFPSLQTVETFTRPEERN
IFSYMMEKHQRNSSANGKIMSYMEQTFLYPSRFDTILYASQLLQAEAMRCGVEHFRRNRG
RCMGTVIWQLNDCWPAASWSSIDYYGRWKALHYYAKRFFAPVLLSCEEEGMLTQDPNVNA
QPCEVRRSIRLNVANETMQTQRGMVIWSLRDPSASIIREESVRIEAGPLSSLWLDKVELP
EAGLFENYVSFRLEADGEILSSGSVLFCAPKYFAFRDPCLQVRAEGEELVVTADAYARSV
EIHNAADDMLLEDNYFDMDAGTRRVKIREGKPEGLTIRSVYDIR

Enzyme Prediction     

No EC number prediction in MGYG000002330_05272.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	654	9.4e-102	0.6156914893617021

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	2.04e-91	21	645	30	635	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340	ebgA	8.44e-14	61	431	113	452	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam17786	Mannosidase_ig	1.17e-10	669	752	3	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
pfam00703	Glyco_hydro_2	3.48e-10	231	297	40	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150	PRK10150	1.27e-08	24	301	46	280	beta-D-glucuronidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADL35923.1	0.0	1	820	1	820
QBE97789.1	0.0	1	824	15	837
QIB54534.1	0.0	1	824	1	823
QMW79049.1	0.0	1	824	1	823
AEF82182.1	0.0	4	824	4	816

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2VJX_A	3.68e-148	6	645	11	657	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	3.89e-148	6	645	13	659	Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
6BYE_A	3.93e-148	6	801	8	825	Crystalstructure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306],6BYE_B Crystal structure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri in complex with mannose [Xanthomonas citri pv. citri str. 306]
7OP6_A	3.99e-148	6	645	13	659	ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
6BYC_A	4.04e-148	6	801	8	825	Crystalstructure of the GH2 exo-beta-mannanase from Xanthomonas axonopodis pv. citri [Xanthomonas citri pv. citri str. 306]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q4WAH4	4.20e-115	6	812	9	833	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
B0YBU9	1.61e-114	6	812	9	833	Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mndB PE=3 SV=1
A1D911	2.34e-113	6	812	9	833	Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1
Q0CCA0	2.52e-110	3	741	6	755	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
A1CGA8	2.64e-110	1	812	4	833	Beta-mannosidase B OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000038	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002330_05272.