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CAZyme Information: MGYG000002334_00379

You are here: Home > Sequence: MGYG000002334_00379

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bifidobacterium thermophilum
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium thermophilum
CAZyme ID MGYG000002334_00379
CAZy Family GT2
CAZyme Description Galactofuranosyltransferase GlfT2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
676 MGYG000002334_1|CGC5 76237.89 6.9372
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002334 2291643 Isolate not provided not provided
Gene Location Start: 472115;  End: 474145  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002334_00379.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT2 214 466 2.7e-45 0.9826086956521739

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1216 GT2 1.04e-39 212 530 2 305
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
pfam13641 Glyco_tranf_2_3 1.61e-35 214 467 3 230
Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.
pfam17994 Glft2_N 9.04e-26 89 203 31 140
Galactofuranosyltransferase 2 N-terminal. This is the N-terminal beta-barrel domain found in the polymerizing galactofuranosyltransferase GlfT2 (Rv3808c). This enzyme synthesizes the bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest component of the mycobacterial cell wall such as in Mycobacterium tuberculosis. The N-terminal domain contains two short helices preceding a 10-stranded beta-sandwich with jelly roll topology.
cd04185 GT_2_like_b 1.68e-18 219 463 3 199
Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
cd02526 GT2_RfbF_like 2.58e-07 219 443 3 204
RfbF is a putative dTDP-rhamnosyl transferase. Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AGH40660.1 0.0 1 676 1 676
QTL79537.1 3.46e-272 14 670 22 683
ADB10612.1 6.92e-272 14 670 12 673
VEG24589.1 9.87e-272 14 670 22 683
BAQ27918.1 9.87e-272 14 670 22 683

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FIX_A 1.22e-114 92 666 62 643
CrystalStructure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIX_B Crystal Structure of GlfT2 [Mycobacterium tuberculosis H37Rv],4FIY_A Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv],4FIY_B Crystal Structure of GlfT2 Complexed with UDP [Mycobacterium tuberculosis H37Rv]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A0R628 2.45e-122 92 668 53 635
Galactofuranosyltransferase GlfT2 OS=Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN=glfT2 PE=3 SV=1
O53585 3.86e-114 92 666 42 623
Galactofuranosyltransferase GlfT2 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=glfT2 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000069 0.000008 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002334_00379.