dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000002334_01617

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Basic Information help

Species

Bifidobacterium thermophilum

Lineage

Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium thermophilum

CAZyme ID

MGYG000002334_01617

CAZy Family

GH18

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
430	MGYG000002334_1\|CGC20	46882.19	4.595

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002334	2291643	Isolate	not provided	not provided

Gene Location

Start: 2061250; End: 2062542 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000002334_01617.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH18	70	332	7.7e-16	0.8648648648648649

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06543	GH18_PF-ChiA-like	5.30e-90	49	355	1	294	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature.
cd12215	ChiC_BD	1.52e-04	382	426	2	42	Chitin-binding domain of chitinase C. Chitin-binding domain of chitinase C (ChiC) of Streptomyces griseus and related proteins. Chitinase C is a family 19 chitinase, and consists of a N-terminal chitin binding domain and a C-terminal chitin-catalytic domain that effects degradation. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source. ChiC contains the characteristic chitin-binding aromatic residues.
cd00598	GH18_chitinase-like	0.001	51	238	2	180	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model.
cd02871	GH18_chitinase_D-like	0.002	50	188	10	145	GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGH41937.1	3.88e-316	1	430	1	430
AUD88803.1	5.61e-204	5	429	2	434
QTL82600.1	1.13e-203	5	429	2	434
AUE20308.1	2.28e-203	5	429	2	434
AUD84704.1	2.28e-203	5	429	2	434

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2DSK_A	4.66e-21	43	324	4	263	Crystalstructure of catalytic domain of hyperthermophilic chitinase from Pyrococcus furiosus [Pyrococcus furiosus],2DSK_B Crystal structure of catalytic domain of hyperthermophilic chitinase from Pyrococcus furiosus [Pyrococcus furiosus]
3A4W_A	2.18e-20	43	324	4	263	Crystalstructures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides [Pyrococcus furiosus],3A4W_B Crystal structures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides [Pyrococcus furiosus]
3A4X_A	5.49e-20	43	324	4	263	Crystalstructures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides [Pyrococcus furiosus],3A4X_B Crystal structures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides [Pyrococcus furiosus],3AFB_A Crystal structures of catalytic site mutants of active domain 2 of chitinase from Pyrococcus furiosus [Pyrococcus furiosus],3AFB_B Crystal structures of catalytic site mutants of active domain 2 of chitinase from Pyrococcus furiosus [Pyrococcus furiosus]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P13656	5.44e-28	74	330	613	869	Probable bifunctional chitinase/lysozyme OS=Escherichia coli (strain K12) OX=83333 GN=chiA PE=1 SV=2
O74199	1.37e-24	74	324	262	509	Endochitinase 11 OS=Metarhizium anisopliae OX=5530 GN=chi11 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.985911	0.005580	0.000395	0.000066	0.000028	0.008039

TMHMM Annotations download full data without filtering help

start	end
13	35