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CAZyme Information: MGYG000002350_00004
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Serratia marcescens_I | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Serratia; Serratia marcescens_I | |||||||||||
| CAZyme ID | MGYG000002350_00004 | |||||||||||
| CAZy Family | GT44 | |||||||||||
| CAZyme Description | Toxin A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 4213; End: 5490 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam12919 | TcdA_TcdB | 1.59e-23 | 21 | 326 | 2 | 316 | TcdA/TcdB catalytic glycosyltransferase domain. This domain represents the N-terminal glycosyltransferase from a set of toxins found in some bacteria. This domain in TcdB glycosylates the host RhoA protein. |
| NF033479 | Efa1_rel_toxin | 2.97e-07 | 2 | 193 | 253 | 510 | LifA/Efa1-related large cytotoxin. Members of this family are large and almost certainly multifunctional proteins found in various pathogens from genus Chlamydia, about 3000 amino acids in size and related to lymphostatin (Efa1/LifA) from enteropathogenic Escherichia coli. Roles have been suggested for Efa1 (EHEC factor for adherence) in adhesion, so some members have been annotated as adherence proteins rather than cytotoxins. |
| pfam04488 | Gly_transf_sug | 4.29e-04 | 166 | 193 | 52 | 79 | Glycosyltransferase sugar-binding region containing DXD motif. The DXD motif is a short conserved motif found in many families of glycosyltransferases, which add a range of different sugars to other sugars, phosphates and proteins. DXD-containing glycosyltransferases all use nucleoside diphosphate sugars as donors and require divalent cations, usually manganese. The DXD motif is expected to play a carbohydrate binding role in sugar-nucleoside diphosphate and manganese dependent glycosyltransferases. |
| COG3774 | OCH1 | 8.91e-04 | 140 | 209 | 121 | 181 | Mannosyltransferase OCH1 or related enzyme [Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVU41152.1 | 0.0 | 1 | 425 | 1 | 425 |
| AVU36050.1 | 0.0 | 1 | 425 | 1 | 425 |
| QOV52705.1 | 1.35e-240 | 1 | 425 | 1 | 425 |
| QLJ31486.1 | 1.57e-239 | 1 | 425 | 1 | 425 |
| QLJ22627.1 | 1.57e-239 | 1 | 425 | 1 | 425 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2VK9_A | 1.49e-21 | 11 | 326 | 90 | 412 | CrystalStructure Of The Catalytic Domain Of Alpha-Toxin From Clostridium Novyi [Clostridium novyi] |
| 3SRZ_A | 9.32e-19 | 22 | 390 | 97 | 487 | ChainA, Toxin A [Clostridioides difficile 630],3SS1_A Chain A, Toxin A [Clostridioides difficile 630] |
| 4DMV_A | 9.34e-19 | 22 | 390 | 112 | 502 | ChainA, Toxin A [Clostridioides difficile],4DMW_A Chain A, Toxin A [Clostridioides difficile] |
| 5UQK_A | 9.38e-19 | 22 | 390 | 97 | 487 | ChainA, Toxin A [Clostridioides difficile],5UQL_A Chain A, Toxin A [Clostridioides difficile] |
| 7U2P_A | 1.62e-18 | 22 | 390 | 98 | 488 | ChainA, Glucosyltransferase TcdA [Clostridioides difficile] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q46149 | 1.63e-20 | 11 | 326 | 90 | 412 | Toxin A OS=Clostridium novyi OX=1542 GN=tcdA PE=1 SV=1 |
| P16154 | 9.71e-18 | 22 | 390 | 97 | 487 | Toxin A OS=Clostridioides difficile OX=1496 GN=tcdA PE=1 SV=2 |
| Q46342 | 5.35e-17 | 22 | 329 | 98 | 413 | Cytotoxin-L OS=Paeniclostridium sordellii OX=1505 GN=tcsL PE=1 SV=1 |
| T0D3N5 | 5.35e-17 | 22 | 329 | 98 | 413 | Cytotoxin-L OS=Paeniclostridium sordellii (strain ATCC 9714 / DSM 2141 / JCM 3814 / LMG 15708 / NCIMB 10717 / 211) OX=1292036 GN=tcsL PE=1 SV=1 |
| P0DUB4 | 9.49e-17 | 22 | 329 | 98 | 413 | Cytotoxin-L OS=Paeniclostridium sordellii OX=1505 GN=tcsL PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000055 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |