Species | Clostridium_F botulinum | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium_F; Clostridium_F botulinum | |||||||||||
CAZyme ID | MGYG000002355_01929 | |||||||||||
CAZy Family | GT1 | |||||||||||
CAZyme Description | Demethyllactenocin mycarosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 1677296; End: 1678477 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT1 | 12 | 385 | 2.5e-39 | 0.93717277486911 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
TIGR01426 | MGT | 3.10e-100 | 7 | 385 | 1 | 388 | glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance] |
COG1819 | YjiC | 2.69e-76 | 1 | 393 | 1 | 405 | UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]. |
cd03784 | GT1_Gtf-like | 4.84e-71 | 3 | 380 | 2 | 399 | UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
cd03785 | GT28_MurG | 2.52e-15 | 13 | 379 | 11 | 344 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
pfam00201 | UDPGT | 1.15e-12 | 270 | 367 | 314 | 419 | UDP-glucoronosyl and UDP-glucosyl transferase. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
AJD26746.1 | 5.10e-284 | 1 | 393 | 1 | 393 |
ACO83590.1 | 7.24e-284 | 1 | 393 | 1 | 393 |
AUN07210.1 | 7.24e-284 | 1 | 393 | 1 | 393 |
CBZ03892.1 | 5.70e-281 | 1 | 393 | 1 | 393 |
APH18787.1 | 9.45e-280 | 1 | 393 | 1 | 393 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
6KQW_A | 5.34e-60 | 4 | 384 | 6 | 382 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
6KQX_A | 6.07e-60 | 4 | 384 | 6 | 382 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
2IYA_A | 1.02e-44 | 4 | 389 | 15 | 422 | Thecrystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus],2IYA_B The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus] |
3IA7_A | 3.69e-38 | 4 | 384 | 7 | 394 | CrystalStructure of CalG4, the Calicheamicin Glycosyltransferase [Micromonospora echinospora],3IA7_B Crystal Structure of CalG4, the Calicheamicin Glycosyltransferase [Micromonospora echinospora] |
3RSC_A | 1.61e-34 | 2 | 384 | 21 | 409 | CrystalStructure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form [Micromonospora echinospora],3RSC_B Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form [Micromonospora echinospora] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
O31853 | 5.13e-62 | 1 | 391 | 1 | 400 | Uncharacterized UDP-glucosyltransferase YojK OS=Bacillus subtilis (strain 168) OX=224308 GN=yojK PE=3 SV=2 |
O34539 | 3.33e-59 | 4 | 384 | 6 | 382 | NDP-glycosyltransferase YjiC OS=Bacillus subtilis (strain 168) OX=224308 GN=yjiC PE=1 SV=1 |
O05496 | 6.28e-56 | 1 | 372 | 1 | 375 | Uncharacterized UDP-glucosyltransferase YdhE OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhE PE=3 SV=2 |
Q65JC2 | 7.36e-54 | 4 | 384 | 6 | 387 | NDP-glycosyltransferase YjiC OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) OX=279010 GN=yjiC PE=1 SV=1 |
Q9XC67 | 2.97e-39 | 1 | 384 | 58 | 454 | Demethyllactenocin mycarosyltransferase OS=Streptomyces fradiae OX=1906 GN=tylCV PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000053 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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